RNA SHAPE Chemistry Reveals Nonhierarchical Interactions Dominate Equilibrium Structural Transitions in tRNA Transcripts.

Current models assume that RNA folding is strongly hierarchical such that the base-paired secondary structure is more stable than and forms independently of the tertiary structure. This model has been difficult to test due to the experimental inability to interrogate the local environment at every n...

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Detalles Bibliográficos

Publicado en:	Journal of the American Chemical Society Vol. 127; no. 13; pp. 4659 - 4668
Autores principales:	Wilkinson, Kevin A., Merino, Edward J., Weeks, Kevin M.
Formato:	Artículo
Publicado:	American Chemical Society 4/6/2005
Materias:	Nucleic acids Transfer RNA Organic compounds Chemical reactions Hydrogen Nucleotides
Acceso en línea:	Ver este registro en EBSCOhost