A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells.

Background: The mechanism of argon laser retinal photocoagulation (ALRP) treatment is to apply thermal-induced retinal pigment epithelium damage. Light passes through the anterior optical segments of the eye to reach the retina. Lens densitometry is a noninvasive and quantitative measurement providi...

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Publicado en:Therapeutic Advances in Ophthalmology pp. 1 - 7
Autores principales: Yılmaz, Uğur, Kaya, Hüseyin, Akbulut, Selen, Durkal, Yasin
Formato: diagnostic images research tables/charts Journal Article
Publicado: Sage Publications Inc. 726/2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 726/2023
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: A cross-sectional study investigating the effects of argon laser retinal photocoagulation on lens clarity and corneal endothelial cells.
      aug:
        au:
          Yılmaz, Uğur
          Kaya, Hüseyin
          Akbulut, Selen
          Durkal, Yasin
        affil: Conceptualization, Ophthalmology Department, Pamukkale University, Denizli 20160, Turkey
      sug:
        subj:
          Eye Surgery Methods
          Retinal Diseases Diagnosis
          Lens Diseases Diagnosis
          Endothelial Cells Pathology
          Lens Diseases Therapy
          Laser Therapy
          Treatment Outcomes
          Human
          Cross Sectional Studies
          Densitometry
          Noninvasive Procedures
          Prospective Studies
          Microscopy
          Endothelial Cells Analysis
          Middle Age
          Corneal Topography
          Middle Aged: 45-64 years
      ab: Background: The mechanism of argon laser retinal photocoagulation (ALRP) treatment is to apply thermal-induced retinal pigment epithelium damage. Light passes through the anterior optical segments of the eye to reach the retina. Lens densitometry is a noninvasive and quantitative measurement providing information about corneal and lens clarity. Objectives: This study aimed to investigate whether laser light affects lens clarity and corneal endothelial cells. Design: This was a prospective, cross-sectional study. Methods: Lens densitometric (LD) analysis and specular microscopy were performed before, after, and 1 month after ALRP treatment, by an expert ophthalmologist, blinded to the medical status of the patients. LD analysis was performed using a Pentacam HR (Oculus, Wetzlar, Germany) and a Specular Microscope CEM-530 (Nidek, Japan) was used for endothelial cell analysis. Results: The evaluation was made on 81 eyes of 41 patients, with a mean age of 54.46 ± 6.7 years. LD, after ALRP, was significantly more than before ALRP (p < 0.001). There was no statistically significant difference in LD, before ALRP, and 1 month after ALRP (p = 0.262). There was a statistically significant increase in LD after ALRP compared to before ALRP, but it decreased after 1 month. There was an increase in the coefficient of variance (CV) after ALRP compared to before ALRP but it was not statistically significant (p = 0.188). There was no statistically significant difference in CV between before ALRP and 1 month after ALRP (p = 1.000). There was no statistically significant difference in the cell density, the hexagonality percentage between before ALRP, after ALRP, and 1 month after ALRP (p = 0.993, and 0.863, respectively). Conclusion: ALRP may affect the lens densitometry temporarily during the procedure. Thermal damage may be the reason for increased lens densitometry.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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