Injection Drug Use and Sexual Risk Behaviors Among People who Inject Drugs in Ukraine: A Random-Intercept Latent Transition Analysis.

HIV transmission in Ukraine is driven in part by unsafe injection drug use and sexual risk behaviors among people who inject drugs. We performed a random-intercept latent transition analysis on responses to 9 binary injection drug use and sexual behavior items from 1195 people who inject drugs with...

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Publicado en:AIDS & Behavior Vol. 27; no. 9; pp. 3012 - 3027
Autores principales: Wiginton, John Mark, Booth, Robert, Eaton, Lisa A., Smith, Laramie R., da Silva, Cristina Espinosa, Patterson, Thomas L., Pitpitan, Eileen V.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Sep2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2023
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      pub: Springer Nature
      place: New York, New York
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        atl: Injection Drug Use and Sexual Risk Behaviors Among People who Inject Drugs in Ukraine: A Random-Intercept Latent Transition Analysis.
      aug:
        au:
          Wiginton, John Mark
          Booth, Robert
          Eaton, Lisa A.
          Smith, Laramie R.
          da Silva, Cristina Espinosa
          Patterson, Thomas L.
          Pitpitan, Eileen V.
        affil: Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California-San Diego, La Jolla, CA, USA
      sug:
        subj:
          Substance Abuse, Intravenous Epidemiology
          Sexual Behavior
          Risk Taking Behavior
          HIV Infections Risk Factors
          Risk Assessment
          Human
          Male
          Female
          Adult
          Persons Who Use Intravenous Drugs
          Ukraine
          Structural Equation Modeling
          Secondary Analysis
          Descriptive Statistics
          Comparative Studies
          Prevalence
          HIV Infections Prevention and Control
          Disease Transmission Prevention and Control
          Funding Source
          Adult: 19-44 years
          Male
          Female
      ab: HIV transmission in Ukraine is driven in part by unsafe injection drug use and sexual risk behaviors among people who inject drugs. We performed a random-intercept latent transition analysis on responses to 9 binary injection drug use and sexual behavior items from 1195 people who inject drugs with negative HIV status enrolled in a clustered randomized clinical trial of a social network intervention in Odessa, Donetsk, and Nikolayev, Ukraine. We identified 5 baseline classes: "Social injection/equipment-sharing" (11.7%), "Social injection" (25.9%), "High-risk collective preparation/splitting" (17.0%), "Collective preparation/splitting" (11.3%), and "Dealer-facilitated injection" (34.1%). After 12 months, intervention participants were more likely to transition to the "Collective preparation/splitting" class, which featured the fewest risk behaviors. Transitioning from the "Collective preparation/splitting" to the "Social injection/equipment-sharing" class was associated with HIV acquisition for control participants. Research to illuminate the stability of these patterns and how they may benefit from uniquely tailored programming to reduce unsafe behaviors is needed.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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