Automated Vowel Articulation Analysis in Connected Speech Among Progressive Neurological Diseases, Dysarthria Types, and Dysarthria Severities.

Purpose: Although articulatory impairment represents distinct speech characteristics in most neurological diseases affecting movement, methods allowing automated assessments of articulation deficits from the connected speech are scarce. This study aimed to design a fully automated method for analyzi...

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Publicado en:Journal of Speech, Language & Hearing Research Vol. 66; no. 8; pp. 2600 - 2622
Autores principales: Illner, Vojtech, Tykalova, Tereza, Skrabal, Dominik, Klempir, Jiri, Rusz, Jan
Formato: Artículo
Publicado: American Speech-Language-Hearing Association Aug2023
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2023
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      pub: American Speech-Language-Hearing Association
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        10.1044/2023_JSLHR-22-00526
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        atl: Automated Vowel Articulation Analysis in Connected Speech Among Progressive Neurological Diseases, Dysarthria Types, and Dysarthria Severities.
      aug:
        au:
          Illner, Vojtech
          Tykalova, Tereza
          Skrabal, Dominik
          Klempir, Jiri
          Rusz, Jan
        affil:
          Department of Circuit Theory, Faculty of Electrical Engineering, Czech Technical University in Prague, Czech Republic.
          Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
          Department of Neurology and ARTORG Center, Inselspital, Bern University Hospital, University of Bern, Switzerland.
      su:
        Speech disorders
        Quantitative research
        Disease risk factors
        Vowels
        Statistics
        Dysarthria
        Neurological disorders
        Fisher exact test
        Severity of illness index
        Automation
        Research funding
        Descriptive statistics
        Sensitivity & specificity (Statistics)
        Data analysis software
        Data analysis
        Algorithms
        Disease complications
      sug:
        subj:
          Speech disorders
          Quantitative research
          Disease risk factors
          Vowels
          Statistics
          Dysarthria
          Neurological disorders
          Fisher exact test
          Severity of illness index
          Automation
          Research funding
          Descriptive statistics
          Sensitivity & specificity (Statistics)
          Data analysis software
          Data analysis
          Algorithms
          Disease complications
      ab: Purpose: Although articulatory impairment represents distinct speech characteristics in most neurological diseases affecting movement, methods allowing automated assessments of articulation deficits from the connected speech are scarce. This study aimed to design a fully automated method for analyzing dysarthria-related vowel articulation impairment and estimate its sensitivity in a broad range of neurological diseases and various types and severities of dysarthria. Method: Unconstrained monologue and reading passages were acquired from 459 speakers, including 306 healthy controls and 153 neurological patients. The algorithm utilized a formant tracker in combination with a phoneme recognizer and subsequent signal processing analysis. Results: Articulatory undershoot of vowels was presented in a broad spectrum of progressive neurodegenerative diseases, including Parkinson's disease, progressive supranuclear palsy, multiple-system atrophy, Huntington's disease, essential tremor, cerebellar ataxia, multiple sclerosis, and amyotrophic lateral sclerosis, as well as in related dysarthria subtypes including hypokinetic, hyperkinetic, ataxic, spastic, flaccid, and their mixed variants. Formant ratios showed a higher sensitivity to vowel deficits than vowel space area. First formants of corner vowels were significantly lower for multiple-system atrophy than cerebellar ataxia. Second formants of vowels /a/ and /i/ were lower in ataxic compared to spastic dysarthria. Discriminant analysis showed a classification score of up to 41.0% for disease type, 39.3% for dysarthria type, and 49.2% for dysarthria severity. Algorithm accuracy reached an F-score of 0.77. Conclusions: Distinctive vowel articulation alterations reflect underlying pathophysiology in neurological diseases. Objective acoustic analysis of vowel articulation has the potential to provide a universal method to screen motor speech disorders.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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