Descriptive Characterization of High-Frequency Distortion Product Otoacoustic Emission Source Components in Children.

Purpose: Distortion product otoacoustic emissions (DPOAEs) provide an objective assessment of cochlear function and are used for serial ototoxicity monitoring in pediatric cancer patients. DPOAEs are modeled as having distortion (near f) and reflection (near 2f-f) component sources, and developmenta...

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Publicado en:Journal of Speech, Language & Hearing Research Vol. 66; no. 8; pp. 2950 - 2967
Autores principales: Dreisbach, Laura, Konrad-Martin, Dawn, Gagner, Christine, Reavis, Kelly M., Jacobs, Peter G.
Formato: Artículo
Publicado: American Speech-Language-Hearing Association Aug2023
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2023
      vid: 66
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      pub: American Speech-Language-Hearing Association
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        10.1044/2023_JSLHR-23-00013
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        atl: Descriptive Characterization of High-Frequency Distortion Product Otoacoustic Emission Source Components in Children.
      aug:
        au:
          Dreisbach, Laura
          Konrad-Martin, Dawn
          Gagner, Christine
          Reavis, Kelly M.
          Jacobs, Peter G.
        affil:
          School of Speech, Language, and Hearing Sciences, San Diego State University, CA.
          National Center for Rehabilitative Auditory Research, VA Portland Health Care System, OR.
          OHSU-PSU School of Public Health, Oregon Health & Science University, Portland.
          Department of Biomedical Engineering, Oregon Health & Science University, Portland.
      su:
        Preschool children
        Children
        Cochlear implants
        Cochlea
        Calibration
        Acoustic nerve
        Impedance audiometry
        Tumors in children
        Comparative studies
        Otoacoustic emissions
        Ototoxicity
        Radio waves
        Diagnosis
        Acoustic nerve diseases
        At-risk people
        Descriptive statistics
        Acoustic stimulation
        Longitudinal method
      sug:
        subj:
          Preschool children
          Children
          Cochlear implants
          Cochlea
          Calibration
          Acoustic nerve
          Impedance audiometry
          Tumors in children
          Comparative studies
          Otoacoustic emissions
          Ototoxicity
          Radio waves
          Diagnosis
          Acoustic nerve diseases
          At-risk people
          Descriptive statistics
          Acoustic stimulation
          Longitudinal method
      ab: Purpose: Distortion product otoacoustic emissions (DPOAEs) provide an objective assessment of cochlear function and are used for serial ototoxicity monitoring in pediatric cancer patients. DPOAEs are modeled as having distortion (near f) and reflection (near 2f-f) component sources, and developmental changes are observed in these components' relative strengths in infants compared with adults. However, little is known about source component strengths in childhood or at extended high frequencies (EHFs; > 8 kHz). Thus, the purpose of this study was to describe the effects of age and stimulus frequency on DPOAE components in children. Method: DPOAEs were collected with varied frequency ratios (f/f = 1.1–1.25) for a wide range of frequencies (2–16 kHz) in 39 younger (3–6 years) and 41 older (10–12 years) children with constant levels (L/L) of 65/50 dB SPL. A depth-compensated simulator sound pressure level method of calibration was employed. A time waveform representation of the results across various ratios was created to estimate peak pressures and latencies of each DPOAE component. Results: Estimated peak pressures of DPOAE components revealed the greatest differences in DPOAE sources between children occurring at the highest frequencies tested, where the peak pressure of both components was largest for younger compared with older children. Latency differences between the children were only noted at higher frequencies for the distortion component. Conclusions: These results suggest that DPOAE levels decrease with age and reflection emissions are vulnerable to cochlear change. This work guides optimization of protocols for pediatric ototoxicity monitoring, whereby including EHF otoacoustic emissions is clearly warranted and choosing to isolate DPOAE sources may prove beneficial.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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