Distinctive visual tasks for characterizing mild cognitive impairment and dementia using oculomotor behavior.
Introduction: One's eye movement (in response to visual tasks) provides a unique window into the cognitive processes and higher-order cognitive functions that become adversely affected in cases with cognitive decline, such as those mild cognitive impairment (MCI) and dementia. MCI is a transitional...
| Publicado en: | Frontiers in Aging Neuroscience pp. 1 - 15 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Frontiers Media S.A.
2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=169779243&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 169779243 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16634365 BG2U jtl: Frontiers in Aging Neuroscience issn: 16634365 maglogo: N pubinfo: dt: 2023 pid: 40038 pub: Frontiers Media S.A. artinfo: ui: 169779243 169779243 169779243 10.3389/fnagi.2023.1125651 169779243 ppf: 1 ppct: 14 formats: tig: atl: Distinctive visual tasks for characterizing mild cognitive impairment and dementia using oculomotor behavior. aug: au: Rane, Dharma Dash, Deba Prasad Dutt, Alakananda Dutta, Anirban Das, Abhijit Lahiri, Uttama affil: Indian Institute of Technology Gandhinagar, Electrical Engineering, Palaj, Gujarat, India sug: subj: Dementia Physiopathology Mild Cognitive Impairment Physiopathology Visual Perception Eye Movements Physiology Task Performance and Analysis Funding Source Human Descriptive Statistics Data Analysis Software Wilcoxon Rank Sum Test Spearman's Rank Correlation Coefficient Male Female Middle Age Middle Aged: 45-64 years Male Female ab: Introduction: One's eye movement (in response to visual tasks) provides a unique window into the cognitive processes and higher-order cognitive functions that become adversely affected in cases with cognitive decline, such as those mild cognitive impairment (MCI) and dementia. MCI is a transitional stage between normal aging and dementia. Methods: In the current work, we have focused on identifying visual tasks (such as horizontal and vertical Pro-saccade, Anti-saccade and Memory Guided Fixation tasks) that can differentiate individuals with MCI and dementia from their cognitively unimpaired healthy aging counterparts based on oculomotor Performance indices. In an attempt to identify the optimal combination of visual tasks that can be used to differentiate the participant groups, clustering was performed using the oculomotor Performance indices. Results: Results of our study with a group of 60 cognitively unimpaired healthy aging individuals, a group with 60 individuals with MCI and a group with 60 individuals with dementia indicate that the horizontal and vertical Anti-saccade tasks provided the optimal combination that could differentiate individuals with MCI and dementia from their cognitively unimpaired healthy aging counterparts with clustering accuracy of -92% based on the saccade latencies. Also, the saccade latencies during both of these Anti-saccade tasks were found to strongly correlate with the Neuropsychological test scores. Discussion: This suggests that the Anti-saccade tasks can hold promise in clinical practice for professionals working with individuals with MCI and dementia. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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