A Patch-Based Deep Learning Approach for Detecting Rib Fractures on Frontal Radiographs in Young Children.

Chest radiography is the modality of choice for the identification of rib fractures in young children and there is value for the development of computer-aided rib fracture detection in this age group. However, the automated identification of rib fractures on chest radiographs can be challenging due...

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Bibliographic Details
Published in:Journal of Digital Imaging Vol. 36; no. 4; pp. 1302 - 1314
Main Authors: Ghosh, Adarsh, Patton, Daniella, Bose, Saurav, Henry, M. Katherine, Ouyang, Minhui, Huang, Hao, Vossough, Arastoo, Sze, Raymond, Sotardi, Susan, Francavilla, Michael
Format: diagnostic images research tables/charts Journal Article
Published: Springer Nature Aug2023
Online Access:View this record in EBSCOhost
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      dt: Aug2023
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      pub: Springer Nature
      place: New York, New York
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        atl: A Patch-Based Deep Learning Approach for Detecting Rib Fractures on Frontal Radiographs in Young Children.
      aug:
        au:
          Ghosh, Adarsh
          Patton, Daniella
          Bose, Saurav
          Henry, M. Katherine
          Ouyang, Minhui
          Huang, Hao
          Vossough, Arastoo
          Sze, Raymond
          Sotardi, Susan
          Francavilla, Michael
        affil: Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA
      sug:
        subj:
          Rib Fractures Radiography
          Deep Learning
          Image Processing, Computer Assisted Methods
          Radiography, Thoracic
          Diagnosis, Computer Assisted
          Algorithms
          Human
          Infant, Newborn
          Infant
          Neural Networks (Computer)
          ROC Curve
          Descriptive Statistics
          Sensitivity and Specificity
          Automation
          Infant, Newborn: birth-1 month
          Infant: 1-23 months
      ab: Chest radiography is the modality of choice for the identification of rib fractures in young children and there is value for the development of computer-aided rib fracture detection in this age group. However, the automated identification of rib fractures on chest radiographs can be challenging due to the need for high spatial resolution in deep learning frameworks. A patch-based deep learning algorithm was developed to automatically detect rib fractures on frontal chest radiographs in children under 2 years old. A total of 845 chest radiographs of children 0–2 years old (median: 4 months old) were manually segmented for rib fractures by radiologists and served as the ground-truth labels. Image analysis utilized a patch-based sliding-window technique, to meet the high-resolution requirements for fracture detection. Standard transfer learning techniques used ResNet-50 and ResNet-18 architectures. Area-under-curve for precision-recall (AUC-PR) and receiver-operating-characteristic (AUC-ROC), along with patch and whole-image classification metrics, were reported. On the test patches, the ResNet-50 model showed AUC-PR and AUC-ROC of 0.25 and 0.77, respectively, and the ResNet-18 showed an AUC-PR of 0.32 and AUC-ROC of 0.76. On the whole-radiograph level, the ResNet-50 had an AUC-ROC of 0.74 with 88% sensitivity and 43% specificity in identifying rib fractures, and the ResNet-18 had an AUC-ROC of 0.75 with 75% sensitivity and 60% specificity in identifying rib fractures. This work demonstrates the utility of patch-based analysis for detection of rib fractures in children under 2 years old. Future work with large cohorts of multi-institutional data will improve the generalizability of these findings to patients with suspicion of child abuse.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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