DeepBLS: Deep Feature-Based Broad Learning System for Tissue Phenotyping in Colorectal Cancer WSIs.

Tissue phenotyping is a fundamental step in computational pathology for the analysis of tumor micro-environment in whole slide images (WSIs). Automatic tissue phenotyping in whole slide images (WSIs) of colorectal cancer (CRC) assists pathologists in better cancer grading and prognostication. In thi...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 4; pp. 1653 - 1663
Autores principales: Baidar Bakht, Ahsan, Javed, Sajid, Gilani, Syed Qasim, Karki, Hamad, Muneeb, Muhammad, Werghi, Naoufel
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Aug2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2023
      vid: 36
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      pub: Springer Nature
      place: New York, New York
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        atl: DeepBLS: Deep Feature-Based Broad Learning System for Tissue Phenotyping in Colorectal Cancer WSIs.
      aug:
        au:
          Baidar Bakht, Ahsan
          Javed, Sajid
          Gilani, Syed Qasim
          Karki, Hamad
          Muneeb, Muhammad
          Werghi, Naoufel
        affil: Electrical and Computer Engineering Department, Khalifa University, 12778, Abu Dhabi, United Arab Emirates
      sug:
        subj:
          Colorectal Neoplasms Pathology
          Tissue Analysis
          Phenotype
          Deep Learning
          Algorithms
          Cell Physiology
          Histology Methods
          Human
          Funding Source
          Pathologists
          Lymphocytes
          Muscle, Smooth
          Models, Statistical
          Descriptive Statistics
          Pathology, Molecular Methods
          Automation, Laboratory
          Neoplasm Grading
          Colorectal Neoplasms Prognosis
          Colorectal Neoplasms Diagnosis
      ab: Tissue phenotyping is a fundamental step in computational pathology for the analysis of tumor micro-environment in whole slide images (WSIs). Automatic tissue phenotyping in whole slide images (WSIs) of colorectal cancer (CRC) assists pathologists in better cancer grading and prognostication. In this paper, we propose a novel algorithm for the identification of distinct tissue components in colon cancer histology images by blending a comprehensive learning system with deep features extraction in the current work. Firstly, we extracted the features from the pre-trained VGG19 network which are then transformed into mapped features space for nodes enhancement generation. Utilizing both mapped features and enhancement nodes, the proposed algorithm classifies seven distinct tissue components including stroma, tumor, complex stroma, necrotic, normal benign, lymphocytes, and smooth muscle. To validate our proposed model, the experiments are performed on two publicly available colorectal cancer histology datasets. We showcase that our approach achieves a remarkable performance boost surpassing existing state-of-the-art methods by (1.3% AvTP, 2% F1) and (7% AvTP, 6% F1) on CRCD-1, and CRCD-2, respectively.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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