Automated Urine Cell Image Classification Model Using Chaotic Mixer Deep Feature Extraction.

Microscopic examination of urinary sediments is a common laboratory procedure. Automated image-based classification of urinary sediments can reduce analysis time and costs. Inspired by cryptographic mixing protocols and computer vision, we developed an image classification model that combines a nove...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 4; pp. 1675 - 1687
Autores principales: Erten, Mehmet, Tuncer, Ilknur, Barua, Prabal D., Yildirim, Kubra, Dogan, Sengul, Tuncer, Turker, Tan, Ru-San, Fujita, Hamido, Acharya, U. Rajendra
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Aug2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2023
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-023-00827-8
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        atl: Automated Urine Cell Image Classification Model Using Chaotic Mixer Deep Feature Extraction.
      aug:
        au:
          Erten, Mehmet
          Tuncer, Ilknur
          Barua, Prabal D.
          Yildirim, Kubra
          Dogan, Sengul
          Tuncer, Turker
          Tan, Ru-San
          Fujita, Hamido
          Acharya, U. Rajendra
        affil: Department of Medical Biochemistry, Malatya Training and Research Hospital, Malatya, Türkiye
      sug:
        subj:
          Algorithms
          Urinalysis Methods
          Microscopy
          Image Processing, Computer Assisted
          Health Care Costs
          Human
          In Vitro Studies
          Diagnosis, Laboratory
          Descriptive Statistics
          Automation, Laboratory
      ab: Microscopic examination of urinary sediments is a common laboratory procedure. Automated image-based classification of urinary sediments can reduce analysis time and costs. Inspired by cryptographic mixing protocols and computer vision, we developed an image classification model that combines a novel Arnold Cat Map (ACM)- and fixed-size patch-based mixer algorithm with transfer learning for deep feature extraction. Our study dataset comprised 6,687 urinary sediment images belonging to seven classes: Cast, Crystal, Epithelia, Epithelial nuclei, Erythrocyte, Leukocyte, and Mycete. The developed model consists of four layers: (1) an ACM-based mixer to generate mixed images from resized 224 × 224 input images using fixed-size 16 × 16 patches; (2) DenseNet201 pre-trained on ImageNet1K to extract 1,920 features from each raw input image, and its six corresponding mixed images were concatenated to form a final feature vector of length 13,440; (3) iterative neighborhood component analysis to select the most discriminative feature vector of optimal length 342, determined using a k-nearest neighbor (kNN)-based loss function calculator; and (4) shallow kNN-based classification with ten-fold cross-validation. Our model achieved 98.52% overall accuracy for seven-class classification, outperforming published models for urinary cell and sediment analysis. We demonstrated the feasibility and accuracy of deep feature engineering using an ACM-based mixer algorithm for image preprocessing combined with pre-trained DenseNet201 for feature extraction. The classification model was both demonstrably accurate and computationally lightweight, making it ready for implementation in real-world image-based urine sediment analysis applications.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
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        Journal Article
      ougenre: Article
    language: English
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