Bayesian Log-Rank Test.

Comparison of two survival curves is a fundamental problem in survival analysis. Although abundant frequentist methods have been developed for comparing survival functions, inference procedures from the Bayesian perspective are rather limited. In this article, we extract the quantity of interest fro...

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Published in:American Statistician Vol. 77; no. 3; pp. 292 - 301
Main Authors: Gu, Jiaqi, Zhang, Yan, Yin, Guosheng
Format: Article
Published: Taylor & Francis Ltd Aug2023
Subjects:
Online Access:View this record in EBSCOhost
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      dt: Aug2023
      vid: 77
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      pub: Taylor & Francis Ltd
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        10.1080/00031305.2022.2161637
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        atl: Bayesian Log-Rank Test.
      aug:
        au:
          Gu, Jiaqi
          Zhang, Yan
          Yin, Guosheng
        affil: Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong, Hong Kong
      su:
        Log-rank test
        Gibbs sampling
        Monte Carlo method
        Survival analysis (Biometry)
        Sampling (Process)
        Censoring (Statistics)
      sug:
        subj:
          Log-rank test
          Gibbs sampling
          Monte Carlo method
          Survival analysis (Biometry)
          Sampling (Process)
          Censoring (Statistics)
      keyword:
        Censored data
        Mixture of Dirichlet processes
        Monte Carlo
        Survival function
        Censored data
        Mixture of Dirichlet processes
        Monte Carlo
        Survival function
      ab: Comparison of two survival curves is a fundamental problem in survival analysis. Although abundant frequentist methods have been developed for comparing survival functions, inference procedures from the Bayesian perspective are rather limited. In this article, we extract the quantity of interest from the classic log-rank test and propose its Bayesian counterpart. Monte Carlo methods, including a Gibbs sampler and a sequential importance sampling procedure, are developed to draw posterior samples of survival functions and a decision rule of hypothesis testing is constructed for making inference. Via simulations and real data analysis, the proposed Bayesian log-rank test is shown to be asymptotically equivalent to the classic one when noninformative prior distributions are used, which provides a Bayesian interpretation of the log-rank test. When using the correct prior information from historical data, the Bayesian log-rank test is shown to outperform the classic one in terms of power. R codes to implement the Bayesian log-rank test are also provided with step-by-step instructions.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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