Aerobic Exercise, Cognitive Performance, and Brain Activity in Adolescents with Attention-Deficit/Hyperactivity Disorder.

Introduction: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder for which behavioral treatments such as exercise are recommended as part of a multidisciplinary treatment program. Exercise improves executive function in individuals with ADHD, but limited information exi...

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Publicado en:Medicine & Science in Sports & Exercise Vol. 55; no. 8; pp. 1445 - 1456
Autores principales: VAN RIPER, STEPHANIE M., TEMPEST, GAVIN D., PICCIRILLI, AARON, QIANHENG, M. A., REISS, ALLAN L.
Formato: diagnostic images research tables/charts randomized controlled trial Journal Article
Publicado: Lippincott Williams & Wilkins Aug2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2023
      vid: 55
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        10.1249/MSS.0000000000003159
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        atl: Aerobic Exercise, Cognitive Performance, and Brain Activity in Adolescents with Attention-Deficit/Hyperactivity Disorder.
      aug:
        au:
          VAN RIPER, STEPHANIE M.
          TEMPEST, GAVIN D.
          PICCIRILLI, AARON
          QIANHENG, M. A.
          REISS, ALLAN L.
        affil: Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA
      sug:
        subj:
          Aerobic Exercises
          Cognition Evaluation
          Brain Physiopathology
          Task Performance and Analysis
          Attention Deficit Hyperactivity Disorder Rehabilitation
          Sitting
          Relaxation
          Treatment Outcomes
          Human
          Child
          Adolescence
          Male
          Female
          Funding Source
          Memory, Short Term Evaluation
          Cycling
          Exercise Intensity
          Descriptive Statistics
          Bicycles
          Randomized Controlled Trials
          Random Assignment
          Comparative Studies
          Prefrontal Cortex Physiopathology
          Magnetic Resonance Imaging
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Introduction: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder for which behavioral treatments such as exercise are recommended as part of a multidisciplinary treatment program. Exercise improves executive function in individuals with ADHD, but limited information exists regarding the mechanisms involved in the response. We examined task-evoked brain responses during exercise and seated rest in 38 adolescents (n = 15 ADHD; age, 13.6 ± 1.9; male, 73.3%; n = 23 typically developing (TD; age, 13.3 ± 2.1; male, 56.5%)). Methods: Participants completed a working memory and inhibitory task while cycling at a moderate intensity for 25 min (i.e., exercise condition) and while seated on the bike without pedaling (i.e., control condition). Conditions were randomized and counterbalanced. Functional near-infrared spectroscopy measured relative changes in oxygenated hemoglobin concentration in 16 brain regions of interest. Brain activity for each cognitive task and condition was examined using linear mixed-effects models with a false discovery rate (FDR) correction. Results: The ADHD group had slower response speeds for all tasks and lower response accuracy in the working memory task during exercise compared with the TD group (P < 0.05). For the inhibitory task, the ADHD group had lower brain activity in the inferior/superior parietal gyrus during exercise compared with the control condition, whereas the opposite was true for TD (FDRcorrected, P < 0.05). For the working memory task, higher brain activity during exercise was observed, regardless of group, in the middle and inferior frontal gyrus and the temporoparietal junction (FDRcorrected, P < 0.05). Conclusions: Dual-task performance is challenging for adolescentswith ADHD, and exercisemaymodulate neuronal resources in regions such as the temporoparietal junction and frontal areas known to be hypoactive in this population. Future research should examine how these relationships change over time.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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