Pill or pump? Nitroglycerin 0.5 mg tablet vs 0.8 mg spray: Effect on proximal vessel diameters at Coronary CT Angiography (CCTA).
The administration of sublingual Nitroglycerin (NTG) prior to CT coronary angiography (CCTA) can be perfomed using pump spray or tablets. Choice of method seems to be based on local preference, rather than published guidelines. This retrospective analysis tested whether proximal coronary diameters d...
| Publicado en: | Radiography Vol. 29; no. 5; pp. 918 - 926 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
W B Saunders
Aug2023
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=169929819&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 169929819 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10788174 DPD jtl: Radiography issn: 10788174 maglogo: N pubinfo: dt: Aug2023 vid: 29 iid: 5 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 169929819 169929819 169929819 10.1016/j.radi.2023.07.004 169929819 ppf: 918 ppct: 8 formats: tig: atl: Pill or pump? Nitroglycerin 0.5 mg tablet vs 0.8 mg spray: Effect on proximal vessel diameters at Coronary CT Angiography (CCTA). aug: au: Kusk, M.W. Bromark, C.S. Hestbek-Møller, M. Davidsen, L.Ø. Precht, H. Brage, K. affil: Imaging Research Initiative SouthWest (IRIS), Esbjerg, Denmark sug: subj: Coronary Vessels Radiography Multidetector Computed Tomography Methods Computed Tomography Angiography Methods Coronary Angiography Methods Coronary Vessels Physiology Nitroglycerin Administration and Dosage Vasodilator Agents Tablets Human Male Female Retrospective Design Analysis of Variance Intraclass Correlation Coefficient Descriptive Statistics Comparative Studies Administration, Sublingual Administration, Oral Male Female ab: The administration of sublingual Nitroglycerin (NTG) prior to CT coronary angiography (CCTA) can be perfomed using pump spray or tablets. Choice of method seems to be based on local preference, rather than published guidelines. This retrospective analysis tested whether proximal coronary diameters differed dependent on the sublingual administration of 0.5 mg Nitroglycerin (NTG) tablets or 0.8 mg NTG spray. 287 ECG-gated CCTA studies with optimal image quality and Agatston scores<400 were included in this retrospective analysis. 143 of the patients were dosed with NTG tablets at a dose of 0.5 mg prior to CCTA. 144 patients received 2 puffs of 0.4 mg NTG spray for a total dose of 8 mg. All were scanned on a second-generation Dual Source CT. Diameters of proximal segments of Left Main (LM), Right (RCA), Left Anterior (LAD) and circumflex (CX) coronary arteries were measured using semi-automatic electronic callipers by two blinded readers. Results were summarised as the mean of maximum and minimum diameters. Sex-specific analysis of diameters was carried out using repeated-measures ANOVA for each vessel. Agreement between readers was examined with Bland-Altman analysis and intra-class-correlation coefficient (ICC). No significant differences in coronary diameters were found except in the RCA for women and LM for men. In both cases, diameters were smaller in the spray group (11 and 9%, respectively). Reader agreement was excellent, with ICC>0.96 for all vessels, and no significant bias, except in CX (0.03 mm). We found no evidence for the systematic superiority of either administration method in proximal coronary vessels. Choosing between tablet or spray NTG prior to CCTA can be guided by practical, economical and hygienic considerations alone. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|