COMPARISON OF MORTALITY IN PATIENTS ON CHEMOTHERAPY OR IMMUNOTHERAPY DURING AND BEFORE COVID-19 PANDEMIC. MULTICENTER MATCHED COHORT STUDY IN ARGENTINA.
Objectives. To compare all-cause mortality of unvaccinated oncology patients who received chemotherapy or immunotherapy during the pandemic with those treated before the pandemic. Materials and methods. We conducted a cohort study in four tertiary hospitals in Argentina. Outpatients with a solid neo...
| Publicado en: | Revista Peruana de Medicina Experimental y Salud Pública Vol. 40; no. 2; pp. 161 - 170 |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | Artículo |
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Instituto Nacional de Salud (Peru)
2023
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=169960985&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 169960985 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 17264634 2WT0 jtl: Revista Peruana de Medicina Experimental y Salud Pública issn: 17264634 maglogo: N pubinfo: dt: 2023 vid: 40 iid: 2 pid: 27380 pub: Instituto Nacional de Salud (Peru) artinfo: ui: 169960985 10.17843/rpmesp.2023.402.12519 ppf: 161 ppct: 9 formats: fmt: @attributes: type: P size: 519KB tig: atl: COMPARISON OF MORTALITY IN PATIENTS ON CHEMOTHERAPY OR IMMUNOTHERAPY DURING AND BEFORE COVID-19 PANDEMIC. MULTICENTER MATCHED COHORT STUDY IN ARGENTINA. aug: au: Itkin, Boris Straminsky, Samanta Cáceres, Hernán Onassis, Mariana Emilio García, Agustín Avanzi, Laura Kaminszczik, Lucia Serna Sejas, Richard Rapaccioli, Mara Billordo, Gustavo Lavaccara, Damián Lanzavecchia, Julián Gibbons, Luz Settecase, Eugenia Bardach, Ariel affil: Oncologist, master in Medical Molecular Biology, Hospital Juan A. Fernández, Buenos Aires, Argentina Oncologist, Hospital Juan A. Fernández, Buenos Aires, Argentina Oncologist, Sanatorio Luis Pasteur, Catamarca, Argentina Pediatric hematologist/oncologist, Sanatorio Luis Pasteur, Catamarca, Argentina Oncologist, Sanatorio Dr. Julio Méndez, Buenos Aires, Argentina Oncologist, Policlínico Modelo de Cipolletti, Rio Negro, Argentina Pulmonologist, Policlínico Modelo de Cipolletti, Rio Negro, Argentina Licentiate in Statistics, Center for Research in Epidemiology and Public Health (CIESP) Instituto de Efectividad Clínica y Sanitaria (IECSCONICET), Buenos Aires, Argentina Doctor of Public Health, Center for Research in Epidemiology and Public Health (CIESP) Instituto de Efectividad Clínica y Sanitaria (IECSCONICET), Buenos Aires, Argentina su: Mortality Cancer chemotherapy Immunotherapy COVID-19 pandemic Body mass index sug: subj: Mortality Cancer chemotherapy Immunotherapy COVID-19 pandemic Body mass index keyword: Cancer Chemotherapy Cohort Studies COVID-19 ab: Objectives. To compare all-cause mortality of unvaccinated oncology patients who received chemotherapy or immunotherapy during the pandemic with those treated before the pandemic. Materials and methods. We conducted a cohort study in four tertiary hospitals in Argentina. Outpatients with a solid neoplasm of any stage under-going cytotoxic or intravenous immunotherapy were eligible. The pandemic cohort was enrolled during the initial phase of the outbreak and compared with a pre-pandemic cohort using propensity score matching (PSM). Subjects were matched for age, sex, health insurance, risk factors for severe COVID-19 complications, performance status, cancer type and treatment, line of treatment, and body mass index. All-cause mortality was estimated for both cohorts after 6 months of follow-up. Results. A total of 169 patients were recruited between April and August 2020 for the pandemic cohort and 377 for the pre-pandemic cohort in the same months of 2019; 168 patients were matched. After PSM, all-cause mortality was 17.9% in the pandemic cohort and 18.5% in the pre-pandemic cohort; the Relative Risk was 0.97 (95 % confidence interval: 0.61-1.52; p=0.888). In the pandemic cohort, 30/168 patients died, but none from COVID-19. Conclusions. Our findings show that the mortality rate of unvaccinated ambulatory patients on active intravenous oncology treatment during the COVID-19 pandemic did not increase. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista Peruana de Medicina Experimental y Salud Pública is the property of Instituto Nacional de Salud (Peru) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista Peruana de Medicina Experimental y Salud Pública holder: Instituto Nacional de Salud (Peru) dt: @attributes: year: 2023 holdings: @attributes: islocal: N |
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