Lipoxygenase inhibiting ethyl substituted glycoside from Symplocos racemosa.

Phytochemical investigation of Symplocos racemosa resulted in the isolation of a new ethyl substituted glycoside, 1-ethyl brachiose-3'-acetate ( 1 ) along with four known compounds ketochaulmoogric acid ( 2 ), nonaeicosanol ( 3 ), triacontyl palmitate ( 4 ) and methyl triacontanoate ( 5 ). The subst...

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Publicado en:Natural Product Research Vol. 19; no. 5; pp. 509 - 516
Autores principales: Abbasi †, Muhammad Athar, Ahmad, Viqar Uddin, Zubair, Muhammad, Nawaz, Sarfraz A., Lodhi, Muhammad Arif, Farooq, Umar, Choudhary, M. Iqbal
Formato: Journal Article
Publicado: Taylor & Francis Ltd Jul2005
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2005
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        10.1080/1478641042000261978
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        atl: Lipoxygenase inhibiting ethyl substituted glycoside from Symplocos racemosa.
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        au:
          Abbasi †, Muhammad Athar
          Ahmad, Viqar Uddin
          Zubair, Muhammad
          Nawaz, Sarfraz A.
          Lodhi, Muhammad Arif
          Farooq, Umar
          Choudhary, M. Iqbal
      sug:
      ab: Phytochemical investigation of Symplocos racemosa resulted in the isolation of a new ethyl substituted glycoside, 1-ethyl brachiose-3'-acetate ( 1 ) along with four known compounds ketochaulmoogric acid ( 2 ), nonaeicosanol ( 3 ), triacontyl palmitate ( 4 ) and methyl triacontanoate ( 5 ). The substitution of ethyl group on 1 was natural because during the course of extraction and purification ethanol was not used. The structural elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The glycoside 1 and triacontyl palmitate ( 4 ) displayed the inhibitory potential against lipoxygenase and urease enzyme, respectively.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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