Dietary acid load in children with chronic kidney disease: its association with nutritional status and health-related quality of life.
Background: This study aimed to determine the dietary acid load of children with chronic kidney disease (CKD) and to evaluate the relationship between dietary acid load, nutritional status, and health-related quality of life (HRQOL). Method: A total of 67 children aged 3–18 years with a diagnosis of...
| Publicado en: | Pediatric Nephrology Vol. 38; no. 10; pp. 3417 - 3427 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=170899562&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 170899562 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0931041X EF1 jtl: Pediatric Nephrology issn: 0931041X maglogo: N pubinfo: dt: Oct2023 vid: 38 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 170899562 163511323 170899562 170899562 10.1007/s00467-023-05991-1 170899562 ppf: 3417 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Dietary acid load in children with chronic kidney disease: its association with nutritional status and health-related quality of life. aug: au: Yurtdaş Depboylu, Gamze Kaner, Gülşah Özdemir Şimşek, Özgür Turan, Kübra Nur Kasap Demir, Belde affil: Department of Nutrition and Dietetics, Faculty of Health Sciences, İzmir Katip Çelebi University, Çiğli Ana Yerleşkesi, Merkezi Ofisler 35620 Çiğli, İzmir, Turkey sug: subj: Renal Insufficiency, Chronic Risk Factors Risk Assessment Acids Adverse Effects Diet Adverse Effects Nutritional Status Food Intake Human Child Male Female Adolescence Scales Child, Preschool Anthropometry Descriptive Statistics Multiple Logistic Regression Odds Ratio Confidence Intervals Glomerular Filtration Rate Albumins Blood Child: 6-12 years Adolescent: 13-18 years Child, Preschool: 2-5 years Male Female ab: Background: This study aimed to determine the dietary acid load of children with chronic kidney disease (CKD) and to evaluate the relationship between dietary acid load, nutritional status, and health-related quality of life (HRQOL). Method: A total of 67 children aged 3–18 years with a diagnosis of CKD stages II–V were included in the study. Anthropometric measurements (body weight, height, mid-upper arm circumference, waist, and neck circumference) and 3-day food consumption records were taken to evaluate the nutritional status. The net endogenous acid production (NEAP) score was calculated to determine the dietary acid load. "Pediatric Inventory of Quality of Life (PedsQL)" was used to assess the participants' HRQOL. Results: The mean NEAP was 59.2 ± 18.96 mEq/day. Stunted and malnourished children had significantly higher NEAP than those who were not (p < 0.05). There were no significant differences in terms of HRQOL scores according to NEAP groups. The multivariate logistic regression analysis showed that waist circumference (OR: 0.890, 95% CI: 0.794–0.997), serum albumin (OR: 0.252, 95% CI: 0.068–0.929), and glomerular filtration rate (GFR) (OR: 0.985, 95% CI: 0.970–1.000) were negatively associated with high NEAP. Conclusion: This study shows that a diet shifted in an acidic direction in children with CKD and a higher dietary acid load are associated with lower serum albumin, GFR, and waist circumference, but not HRQOL. These results suggest that dietary acid load might affect nutritional status and CKD progression in children with CKD. Future studies with larger samples are needed to confirm these results and to understand underlying mechanisms. A higher resolution version of the Graphical abstract is available as Supplementary information pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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