Associations Between Core Temperature Disorders and Outcomes of Pediatric Intensive Care Unit Patients.

Background: The few studies of associations between fever and outcomes in pediatric intensive care unit (PICU) patients have conflicting findings. Associations between hypothermia and patient outcomes have not been studied. Objective: To investigate the incidence and characteristics of fever and hyp...

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Publicado en:American Journal of Critical Care Vol. 32; no. 5; pp. 338 - 346
Autores principales: Kiekkas, Panagiotis, Kourtis, Grigorios, Feizidou, Paraskevi, Igoumenidis, Michael, Almpani, Eleni, Tzenalis, Anastasios
Formato: research tables/charts Journal Article
Publicado: American Association of Critical-Care Nurses Sep2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2023
      vid: 32
      iid: 5
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      pub: American Association of Critical-Care Nurses
      place: Alisa Veijo, California
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        atl: Associations Between Core Temperature Disorders and Outcomes of Pediatric Intensive Care Unit Patients.
      aug:
        au:
          Kiekkas, Panagiotis
          Kourtis, Grigorios
          Feizidou, Paraskevi
          Igoumenidis, Michael
          Almpani, Eleni
          Tzenalis, Anastasios
        affil: Panagiotis Kiekkas is a professor in the Nursing Department, University of Patras, Greece
      sug:
        subj:
          Fever Epidemiology
          Hypothermia Epidemiology
          Disease Attributes
          Hospital Mortality Risk Factors
          Risk Assessment
          Intensive Care Units, Pediatric
          Human
          Male
          Female
          Child, Preschool
          Child
          Adolescence
          Prospective Studies
          Thermometers
          Body Temperature
          Descriptive Statistics
          Comparative Studies
          Incidence
          Retrospective Design
          Respiration, Artificial
          Length of Stay
          Multivariate Analysis
          Univariate Statistics
          Nonexperimental Studies
          Convenience Sample
          Tertiary Health Care Greece
          Greece
          Data Analysis Software
          Critical Illness Mortality
          Odds Ratio
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Background: The few studies of associations between fever and outcomes in pediatric intensive care unit (PICU) patients have conflicting findings. Associations between hypothermia and patient outcomes have not been studied. Objective: To investigate the incidence and characteristics of fever and hypothermia and their associations with adverse outcomes among PICU patients. Methods: Patients consecutively admitted to 2 PICUs in a 2-year period were prospectively studied. Core temperature was mainly measured by rectal or axillary thermometry. Fever and hypothermia were defined as core temperatures of greater than 38.0 °C and less than 36.0 °C, respectively. Prolonged mechanical ventilation, prolonged PICU stay, and PICU mortality were the adverse patient outcomes studied. Associations between patient outcomes and core temperature disorders were evaluated with univariate comparisons and multivariate analyses. Results: Of 545 patients enrolled, fever occurred in 299 (54.9%) and hypothermia occurred in 161 (29.5%). Both temperature disorders were independently associated with prolonged mechanical ventilation and prolonged PICU stay (P <.001) but not with PICU mortality. Late onset of fever (P <.001) and hypothermia (P =.009) were independently associated with prolonged mechanical ventilation, fever magnitude and duration (both P <.001) were independently associated with prolonged PICU stay, and fever magnitude (P <.001) and infectious cause of hypothermia (P=.01) were independently associated with higher PICU mortality. Conclusions: These findings provide evidence that the manifestation and characteristics of fever and hypothermia are independent predictors of adverse outcomes in PICU patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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