Demonstration of subclinical left ventricular electrical and mechanical dysfunction in overweight subjects by frontal QRS‐T angle and 3D‐speckle tracking echocardiography.

Background: Overweightness is a considerable step in the process leading to obesity. There are no sufficient studies on the effect of cardiomyopathy defined in obese patients about overweight subjects. We thought that it may be useful to examine the myocardial involvement in overweight individuals e...

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Publicado en:Echocardiography Vol. 40; no. 9; pp. 969 - 976
Autores principales: Mammadov, Ganbar, Taskin, Ugur, Dindas, Ferhat, Dogdus, Mustafa
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Sep2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.15667
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        atl: Demonstration of subclinical left ventricular electrical and mechanical dysfunction in overweight subjects by frontal QRS‐T angle and 3D‐speckle tracking echocardiography.
      aug:
        au:
          Mammadov, Ganbar
          Taskin, Ugur
          Dindas, Ferhat
          Dogdus, Mustafa
        affil: Faculty of Medicine, Department of Cardiology, Izmir University of Economics, Izmir, Turkey
      sug:
        subj:
          Heart Ventricle, Left Physiology
          Obesity
          Ventricular Dysfunction, Left
          QRS Complex
          Echocardiography, Three-Dimensional
          Human
          Body Mass Index
          Echocardiography Methods
          Aged, 80 and Over
          Sex Factors
          Descriptive Statistics
          Aged, 80 & over
      ab: Background: Overweightness is a considerable step in the process leading to obesity. There are no sufficient studies on the effect of cardiomyopathy defined in obese patients about overweight subjects. We thought that it may be useful to examine the myocardial involvement in overweight individuals electro‐mechanically with more sensitive techniques before the development of obesity cardiomyopathy. Aim: The aim of the present study was to demonstrate whether or not there are subclinical left ventricular (LV) electrical and mechanical dysfunctions in overweight patients using frontal QRS‐T (fQRS‐T) angle (electrically) and 3D‐speckle tracking echocardiography (mechanically). Methods: A total of 80 overweight patients and 80 age‐ and sex‐matched normal weight individuals were enrolled into the study. 3D‐STE examinations of the patients were performed. Electrocardiographic recordings were obtained for fQRS‐T angle assessment. Results: The LV‐GLS and LV‐GCS were significantly depressed in the overweight group than in the normal weight group (−14.5 ± 3.4 vs. −21.7 ± 3.6, p <.001; −15.2 ± 4.6 vs. −24.3 ± 4.8, p <.001, respectively). The fQRS‐T angle was found to be increased in the overweight group (142.5 ± 39.2 vs. 114.7 ± 43.5, p = <.001). Statistically significant positive linear correlations were observed between BMI with LV‐GLS, LV‐GCS, and fQRS‐T angle. LV‐GLS and LV‐GCS were found to be disrupted linearly as BMI increased (r =.718 for BMI and LV‐GLS, r =.653 for BMI and LV‐GCS). As BMI increased, it was found that the fQRS‐T angle increased (r =.692 for BMI and fQRS‐T angle). Conclusion: Our results support that, overweight individuals, despite their being apparently healthy, may have subclinical LV myocardial mechanical and electrical dysfunction.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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