Comparison of 1.5 T and 3 T magnetic resonance angiography for detecting cerebral aneurysms using deep learning-based computer-assisted detection software.

Purpose: To compare the diagnostic performance of 1.5 T versus 3 T magnetic resonance angiography (MRA) for detecting cerebral aneurysms with clinically available deep learning-based computer-assisted detection software (EIRL aneurysm® [EIRL_an]), which has been approved by the Japanese Pharmaceutic...

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Publicado en:Neuroradiology Vol. 65; no. 10; pp. 1473 - 1483
Autores principales: Tajima, Taku, Akai, Hiroyuki, Yasaka, Koichiro, Kunimatsu, Akira, Yoshioka, Naoki, Akahane, Masaaki, Ohtomo, Kuni, Abe, Osamu, Kiryu, Shigeru
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2023
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00234-023-03216-8
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        atl: Comparison of 1.5 T and 3 T magnetic resonance angiography for detecting cerebral aneurysms using deep learning-based computer-assisted detection software.
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          Tajima, Taku
          Akai, Hiroyuki
          Yasaka, Koichiro
          Kunimatsu, Akira
          Yoshioka, Naoki
          Akahane, Masaaki
          Ohtomo, Kuni
          Abe, Osamu
          Kiryu, Shigeru
        affil: Department of Radiology, International University of Health and Welfare Mita Hospital, 1-4-3 Mita, Minato-Ku, 108-8329, Tokyo, Japan
      sug:
        subj:
          Magnetic Resonance Angiography Equipment and Supplies
          Cerebral Aneurysm Diagnosis
          Deep Learning
          False Positive Results
          Human
          Retrospective Design
          Pearson's Correlation Coefficient
          Fisher's Exact Test
          Mann-Whitney U Test
          Male
          Female
          Descriptive Statistics
          Middle Age
          Aged
          Aged, 80 and Over
          Funding Source
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Purpose: To compare the diagnostic performance of 1.5 T versus 3 T magnetic resonance angiography (MRA) for detecting cerebral aneurysms with clinically available deep learning-based computer-assisted detection software (EIRL aneurysm® [EIRL_an]), which has been approved by the Japanese Pharmaceuticals and Medical Devices Agency. We also sought to analyze the causes of potential false positives. Methods: In this single-center, retrospective study, we evaluated the MRA scans of 90 patients who underwent head MRA (1.5 T and 3 T in 45 patients each) in clinical practice. Overall, 51 patients had 70 aneurysms. We used MRI from a vendor not included in the dataset used to create the EIRL_an algorithm. Two radiologists determined the ground truth, the accuracy of the candidates noted by EIRL_an, and the causes of false positives. The sensitivity, number of false positives per case (FPs/case), and the causes of false positives were compared between 1.5 T and 3 T MRA. Pearson's χ2 test, Fisher's exact test, and the Mann‒Whitney U test were used for the statistical analyses as appropriate. Results: The sensitivity was high for 1.5 T and 3 T MRA (0.875‒1), but the number of FPs/case was significantly higher with 3 T MRA (1.511 vs. 2.578, p < 0.001). The most common causes of false positives (descending order) were the origin/bifurcation of vessels/branches, flow-related artifacts, and atherosclerosis and were similar between 1.5 T and 3 T MRA. Conclusion: EIRL_an detected significantly more false-positive lesions with 3 T than with 1.5 T MRA in this external validation study. Our data may help physicians with limited experience with MRA to correctly diagnose aneurysms using EIRL_an.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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