Automatic Image Segmentation and Grading Diagnosis of Sacroiliitis Associated with AS Using a Deep Convolutional Neural Network on CT Images.

Ankylosing spondylitis (AS) is a chronic inflammatory disease that causes inflammatory low back pain and may even limit activity. The grading diagnosis of sacroiliitis on imaging plays a central role in diagnosing AS. However, the grading diagnosis of sacroiliitis on computed tomography (CT) images...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 5; pp. 2025 - 2035
Autores principales: Zhang, Ke, Luo, Guibo, Li, Wenjuan, Zhu, Yunfei, Pan, Jielin, Li, Ximeng, Liu, Chaoran, Liang, Jianchao, Zhan, Yingying, Zheng, Jing, Li, Shaolin, Cai, Wenli, Hong, Guobin
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        10.1007/s10278-023-00858-1
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        atl: Automatic Image Segmentation and Grading Diagnosis of Sacroiliitis Associated with AS Using a Deep Convolutional Neural Network on CT Images.
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          Zhang, Ke
          Luo, Guibo
          Li, Wenjuan
          Zhu, Yunfei
          Pan, Jielin
          Li, Ximeng
          Liu, Chaoran
          Liang, Jianchao
          Zhan, Yingying
          Zheng, Jing
          Li, Shaolin
          Cai, Wenli
          Hong, Guobin
        affil: https://ror.org/0064kty71 Department of Radiology, the Fifth Affiliated Hospital, Sun Yat-Sen University, 519000, Zhuhai, China
      sug:
        subj:
          Sacroiliitis Diagnosis
          Spondylitis, Ankylosing Diagnosis
          Spondylitis, Ankylosing Complications
          Image Processing, Computer Assisted Methods
          Convolutional Neural Networks
          Sacroiliac Joint Pathology
          Sacroiliac Joint Radiography
          Tomography, X-Ray Computed
          Automation
          Deep Learning
          Sacroiliitis Radiography
          Retrospective Design
          Radiologists
          Human
          Male
          Female
          Adult
          Middle Age
          Data Analysis Software
          Descriptive Statistics
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Ankylosing spondylitis (AS) is a chronic inflammatory disease that causes inflammatory low back pain and may even limit activity. The grading diagnosis of sacroiliitis on imaging plays a central role in diagnosing AS. However, the grading diagnosis of sacroiliitis on computed tomography (CT) images is viewer-dependent and may vary between radiologists and medical institutions. In this study, we aimed to develop a fully automatic method to segment sacroiliac joint (SIJ) and further grading diagnose sacroiliitis associated with AS on CT. We studied 435 CT examinations from patients with AS and control at two hospitals. No-new-UNet (nnU-Net) was used to segment the SIJ, and a 3D convolutional neural network (CNN) was used to grade sacroiliitis with a three-class method, using the grading results of three veteran musculoskeletal radiologists as the ground truth. We defined grades 0–I as class 0, grade II as class 1, and grades III–IV as class 2 according to modified New York criteria. nnU-Net segmentation of SIJ achieved Dice, Jaccard, and relative volume difference (RVD) coefficients of 0.915, 0.851, and 0.040 with the validation set, respectively, and 0.889, 0.812, and 0.098 with the test set, respectively. The areas under the curves (AUCs) of classes 0, 1, and 2 using the 3D CNN were 0.91, 0.80, and 0.96 with the validation set, respectively, and 0.94, 0.82, and 0.93 with the test set, respectively. 3D CNN was superior to the junior and senior radiologists in the grading of class 1 for the validation set and inferior to expert for the test set (P < 0.05). The fully automatic method constructed in this study based on a convolutional neural network could be used for SIJ segmentation and then accurately grading and diagnosis of sacroiliitis associated with AS on CT images, especially for class 0 and class 2. The method for class 1 was less effective but still more accurate than that of the senior radiologist.
      pubtype: Academic Journal
      doctype:
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        research
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    language: English
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