COVID-19 Severity Prediction from Chest X-ray Images Using an Anatomy-Aware Deep Learning Model.

The COVID-19 pandemic has been adversely affecting the patient management systems in hospitals around the world. Radiological imaging, especially chest x-ray and lung Computed Tomography (CT) scans, plays a vital role in the severity analysis of hospitalized COVID-19 patients. However, with an incre...

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Detalles Bibliográficos
Publicado en:Journal of Digital Imaging Vol. 36; no. 5; pp. 2100 - 2113
Autores principales: Nizam, Nusrat Binta, Siddiquee, Sadi Mohammad, Shirin, Mahbuba, Bhuiyan, Mohammed Imamul Hassan, Hasan, Taufiq
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Oct2023
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The COVID-19 pandemic has been adversely affecting the patient management systems in hospitals around the world. Radiological imaging, especially chest x-ray and lung Computed Tomography (CT) scans, plays a vital role in the severity analysis of hospitalized COVID-19 patients. However, with an increasing number of patients and a lack of skilled radiologists, automated assessment of COVID-19 severity using medical image analysis has become increasingly important. Chest x-ray (CXR) imaging plays a significant role in assessing the severity of pneumonia, especially in low-resource hospitals, and is the most frequently used diagnostic imaging in the world. Previous methods that automatically predict the severity of COVID-19 pneumonia mainly focus on feature pooling from pre-trained CXR models without explicitly considering the underlying human anatomical attributes. This paper proposes an anatomy-aware (AA) deep learning model that learns the generic features from x-ray images considering the underlying anatomical information. Utilizing a pre-trained model and lung segmentation masks, the model generates a feature vector including disease-level features and lung involvement scores. We have used four different open-source datasets, along with an in-house annotated test set for training and evaluation of the proposed method. The proposed method improves the geographical extent score by 11% in terms of mean squared error (MSE) while preserving the benchmark result in lung opacity score. The results demonstrate the effectiveness of the proposed AA model in COVID-19 severity prediction from chest X-ray images. The algorithm can be used in low-resource setting hospitals for COVID-19 severity prediction, especially where there is a lack of skilled radiologists.