Quantitative Validation of the Correlation Between Optimized Pyramidal Tract Delineation After Brain Shift Compensation and Direct Electrical Subcortical Stimulation During Brain Tumor Surgery.

It remains unclear whether tractography of pyramidal tracts is correlated with the intraoperative direct electrical subcortical stimulation (DESS), and brain shift further complicates the issue. The objective of this research is to quantitatively verify the correlation between optimized tractography...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 5; pp. 1974 - 1987
Autores principales: Li, Ye, Hou, Yuanzheng, Li, Xiaoyu, Li, Qiongge, Lu, Jie, Tang, Jie
Formato: algorithm diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        10.1007/s10278-023-00867-0
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        atl: Quantitative Validation of the Correlation Between Optimized Pyramidal Tract Delineation After Brain Shift Compensation and Direct Electrical Subcortical Stimulation During Brain Tumor Surgery.
      aug:
        au:
          Li, Ye
          Hou, Yuanzheng
          Li, Xiaoyu
          Li, Qiongge
          Lu, Jie
          Tang, Jie
        affil: https://ror.org/013xs5b60 Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, 100853, Xicheng District, Beijing, China
      sug:
        subj:
          Brain Neoplasms Surgery
          Brain Surgery Methods
          Deep Brain Stimulation Methods
          Brain Radiography
          Neural Pathways Radiography
          Magnetic Resonance Imaging Methods
          Intraoperative Monitoring
          Human
          Correlational Studies
          Treatment Outcomes
          Intraoperative Complications Prevention and Control
          Postoperative Complications Prevention and Control
          Preoperative Period
          Algorithms
          Evoked Potentials
          ROC Curve
          Cancer Patients
          Brain Neoplasms Radiography
          Funding Source
      ab: It remains unclear whether tractography of pyramidal tracts is correlated with the intraoperative direct electrical subcortical stimulation (DESS), and brain shift further complicates the issue. The objective of this research is to quantitatively verify the correlation between optimized tractography (OT) of pyramidal tracts after brain shift compensation and DESS during brain tumor surgery. OT was performed for 20 patients with lesions in proximity to the pyramidal tracts based on preoperative diffusion-weighted magnetic resonance imaging. During surgery, tumor resection was guided by DESS. A total of 168 positive stimulation points and their corresponding stimulation intensity thresholds were recorded. Using the brain shift compensation algorithm based on hierarchical B-spline grids combined with a Gaussian resolution pyramid, we warped the preoperative pyramidal tract models and used receiver operating characteristic (ROC) curves to investigate the reliability of our brain shift compensation method based on anatomic landmarks. Additionally, the minimum distance between the DESS points and warped OT (wOT) model was measured and correlated with DESS intensity threshold. Brain shift compensation was achieved in all cases, and the area under the ROC curve was 0.96 in the registration accuracy analysis. The minimum distance between the DESS points and the wOT model was found to have a significantly high correlation with the DESS stimulation intensity threshold (r = 0.87, P < 0.001), with a linear regression coefficient of 0.96. Our OT method can provide comprehensive and accurate visualization of the pyramidal tracts for neurosurgical navigation and was quantitatively verified by intraoperative DESS after brain shift compensation.
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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