A Domain-Shift Invariant CNN Framework for Cardiac MRI Segmentation Across Unseen Domains.

The emergence of various deep learning approaches in diagnostic medical image segmentation has made machines capable of accomplishing human-level accuracy. However, the generalizability of these architectures across patients from different countries, Magnetic Resonance Imaging (MRI) scans from disti...

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Publicado en:Journal of Digital Imaging Vol. 36; no. 5; pp. 2148 - 2164
Autores principales: Patil, Sanjeet S., Ramteke, Manojkumar, Verma, Mansi, Seth, Sandeep, Bhargava, Rohit, Mittal, Shachi, Rathore, Anurag S.
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2023
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-023-00873-2
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        atl: A Domain-Shift Invariant CNN Framework for Cardiac MRI Segmentation Across Unseen Domains.
      aug:
        au:
          Patil, Sanjeet S.
          Ramteke, Manojkumar
          Verma, Mansi
          Seth, Sandeep
          Bhargava, Rohit
          Mittal, Shachi
          Rathore, Anurag S.
        affil: https://ror.org/049tgcd06 Department of Chemical Engineering, Indian Institute of Technology, Delhi, New Delhi, India
      sug:
        subj:
          Magnetic Resonance Imaging
          Deep Learning
          Conceptual Framework
          Neural Networks (Computer)
          Heart
          Human
          Ventricular Ejection Fraction
          Systole
          India
          Stroke Volume
      ab: The emergence of various deep learning approaches in diagnostic medical image segmentation has made machines capable of accomplishing human-level accuracy. However, the generalizability of these architectures across patients from different countries, Magnetic Resonance Imaging (MRI) scans from distinct vendors, and varying imaging conditions remains questionable. In this work, we propose a translatable deep learning framework for diagnostic segmentation of cine MRI scans. This study aims to render the available SOTA (state-of-the-art) architectures domain-shift invariant by utilizing the heterogeneity of multi-sequence cardiac MRI. To develop and test our approach, we curated a diverse group of public datasets and a dataset obtained from private source. We evaluated 3 SOTA CNN (Convolution neural network) architectures i.e., U-Net, Attention-U-Net, and Attention-Res-U-Net. These architectures were first trained on a combination of three different cardiac MRI sequences. Next, we examined the M&M (multi-center & mutli-vendor) challenge dataset to investigate the effect of different training sets on translatability. The U-Net architecture, trained on the multi-sequence dataset, proved to be the most generalizable across multiple datasets during validation on unseen domains. This model attained mean dice scores of 0.81, 0.85, and 0.83 for myocardial wall segmentation after testing on unseen MyoPS (Myocardial Pathology Segmentation) 2020 dataset, AIIMS (All India Institute of Medical Sciences) dataset and M&M dataset, respectively. Our framework achieved Pearson's correlation values of 0.98, 0.99, and 0.95 between the observed and predicted parameters of end diastole volume, end systole volume, and ejection fraction, respectively, on the unseen Indian population dataset.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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