Sleep Assessment in Critically Ill Patients With Acute Hypoxemic Respiratory Failure.
Background: Sleep deprivation alters respiratory muscle performance and may precipitate respiratory failure. This study aimed to assess sleep in subjects admitted to ICU for acute hypoxemic respiratory failure and its role in the risk of intubation. Methods: This was a prospective observational sing...
| Publicado en: | Respiratory Care Vol. 68; no. 10; pp. 1417 - 1426 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Oct2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=172028565&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 172028565 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Oct2023 vid: 68 iid: 10 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 172028565 172028565 172028565 10.4187/respcare.10844 172028565 ppf: 1417 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Sleep Assessment in Critically Ill Patients With Acute Hypoxemic Respiratory Failure. aug: au: Thille, Arnaud W. Marie, Damien Reynaud, Faustine Barrau, Stéphanie Beuvon, Clément Bironneau, Vanessa Jutant, Etienne-Marie Coudroy, Rémi Frat, Jean-Pierre Rault, Christophe Drouot, Xavier affil: INSERM CIC 1402, ALIVE Research Group, University of Poitiers, Poitiers, France sug: subj: Sleep Deprivation Evaluation Anoxemia Physiopathology Respiratory Failure Physiopathology Intubation Critically Ill Patients Human Male Female Middle Age Aged Prospective Studies Nonexperimental Studies Intensive Care Units Polysomnography Sleep Duration Evaluation Sleep Quality Evaluation Sleep, REM Kaplan-Meier Estimator Fisher's Exact Test Mann-Whitney U Test Descriptive Statistics Data Analysis Software Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Background: Sleep deprivation alters respiratory muscle performance and may precipitate respiratory failure. This study aimed to assess sleep in subjects admitted to ICU for acute hypoxemic respiratory failure and its role in the risk of intubation. Methods: This was a prospective observational single-center cohort study including subjects admitted to ICU for de novo acute hypoxemic respiratory failure defined as breathing frequency ≥ 25 breaths/min or clinical signs of respiratory distress and ... < 300 mm Hg while receiving high-flow nasal oxygen. Subjects with altered consciousness, central nervous or psychiatric disorders, continuous sedation or neuroleptic medication, or were uncooperative were excluded. Sleep was assessed by complete polysomnography (PSG) the night following ICU admission. The main outcome was to assess sleep among subjects with acute hypoxemic respiratory failure and to compare sleep between subjects who eventually required intubation to those who did not. Results: Over a 24-month inclusion period, 34 subjects had complete PSG, among whom 5 (15%) required intubation in the ICU. Total sleep time was 4.2 h in median (interquartile range 2.9-6.8); deep-sleep duration was 70 min (34-127), and rapid eye movement (REM) sleep duration was 9 min (0-28). Among them, 13 subjects (38%) had no REM sleep. Total sleep time and duration of deep and REM sleep stages did not differ between subjects who required intubation and those successfully treated with high-flow nasal oxygen. Conclusions: Whereas total sleep time remained relatively preserved in critically ill subjects with acute hypoxemic respiratory failure, REM sleep time was uncommon or completely absent in a large number of subjects. Sleep did not differ between subjects who required intubation and those who did not. However, given a trend toward an increased risk of intubation in subjects with a complete absence of REM sleep, further studies are needed to better explore the impact of REM sleep on the risk of intubation. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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