Development of Anti-TNF-A Treatment Adherence Scale: Patients with Rheumatic Disease.

Background: In recent years, there has been an increase in the use of anti-TNF-α therapies in the treatment of rheumatological diseases. Aim: The aim of this study was to develop a subcutaneous anti- TNF-α treatment adherence scale and investigate and confirm the reliability and validity of this new...

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Publicado en:International Journal of Caring Sciences Vol. 16; no. 2; pp. 829 - 840
Autores principales: Ozkaraman, Ayse, Uzgor, Fusun, Atalay, Hatice Ozden, Yasar Bilge, Nazife Sule, Kasifoglu, Timucin
Formato: research tables/charts Journal Article
Publicado: International Journal of Caring Sciences May-Aug2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May-Aug2023
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      pub: International Journal of Caring Sciences
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        atl: Development of Anti-TNF-A Treatment Adherence Scale: Patients with Rheumatic Disease.
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        au:
          Ozkaraman, Ayse
          Uzgor, Fusun
          Atalay, Hatice Ozden
          Yasar Bilge, Nazife Sule
          Kasifoglu, Timucin
        affil: Associate Professor, Eskisehir Osmangazi University Faculty of Health Sciences, Nursing Department, Eskisehir, Turkey
      sug:
        subj:
          Tumor Necrosis Factor Inhibitors Immunology
          Instrument Construction
          Rheumatic Diseases Diagnosis
          Human
          Male
          Female
          Scales
          Methodological Research
          Reliability and Validity
          Test-Retest Reliability
          Factor Analysis
          Structural Equation Modeling
          Internal Consistency
          Coefficient alpha
          Funding Source
          Male
          Female
      ab: Background: In recent years, there has been an increase in the use of anti-TNF-α therapies in the treatment of rheumatological diseases. Aim: The aim of this study was to develop a subcutaneous anti- TNF-α treatment adherence scale and investigate and confirm the reliability and validity of this new instrument. This methodological study was performed in an university hospitals between April 2018 and March 2019. The sample of the study (n:165) consisted of individuals who were completed the first month of SC anti TNF-α treatment. The research data were collected by using an individual introduction form and the newly developed Anti TNF-α Treatment Adherence Scale. In the analysis of the data, the test-retest reliability analysis, validity analysis, factor analysis, structural equation model and internal consistency analysis were used. Results: The item-total test correlation values were determined to be between 0.33 and 0.71. In the fit index calculations, it was found that the Root Mean Square Error of Approximation was 0.10, Goodness of Fit Index was 0.999, Adjusted Goodness of Fit Index was 0.998, Comparative Fit Index was 0.926; and χ² was 2.670 (p<0.001). Cronbach α coefficient was calculated as 0.690 for factor 1, 0.765 for factor 2, 0.628 for factor 3 and 0.671 for the overall scale. Conclusion: In this study, Anti TNF-α Treatment Adherence Scale was determined that it is a valid and reliable scale. It is the first assessment tool that can be used in the evaluation of drug adherence in SC Anti-TNF-α treatment performed by patients / their relatives due to rheumatologic and all inflammatory diseases.
      pubtype: Academic Journal
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        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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