A population-based descriptive study of neonatal abstinence syndrome using hospital discharge and birth certificate data.

Neonatal abstinence syndrome (NAS), largely a consequence of prenatal opioid exposure, results in substantial morbidity. Population-based studies of NAS going beyond Medicaid populations and hospital discharge data (HDD) alone are limited. Using statewide Tennessee (TN) HDD and birth certificate (BC...

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Publicado en:Journal of Substance Use Vol. 28; no. 5; pp. 789 - 797
Autores principales: Rainey, Jacob C., Satcher, Lacee, Nechuta, Sarah J.
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2023
      vid: 28
      iid: 5
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      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
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        10.1080/14659891.2022.2098841
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        atl: A population-based descriptive study of neonatal abstinence syndrome using hospital discharge and birth certificate data.
      aug:
        au:
          Rainey, Jacob C.
          Satcher, Lacee
          Nechuta, Sarah J.
        affil: Bloomberg School of Public Health, Department of Mental Health, Johns Hopkins University, Baltimore, Maryland, USA
      sug:
        subj:
          Neonatal Abstinence Syndrome Diagnosis
          Neonatal Abstinence Syndrome Trends
          Neonatal Abstinence Syndrome Epidemiology
          Birth Certificates Statistics and Numerical Data
          Patient Discharge Statistics and Numerical Data
          Maternal-Child Health
          Descriptive Research
          Retrospective Design
          Prospective Studies
          Prenatal Exposure Delayed Effects
          Analgesics, Opioid Adverse Effects
          International Classification of Diseases
          Outcomes (Health Care)
          Multivariate Analysis
          Logistic Regression
          Confidence Intervals
          Odds Ratio
          Prenatal Care
          Sample Size
          Human
          Male
          Female
          Adolescence
          Young Adult
          Adult
          Middle Age
          Data Analysis Software
          Funding Source
          Descriptive Statistics
          Chi Square Test
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Neonatal abstinence syndrome (NAS), largely a consequence of prenatal opioid exposure, results in substantial morbidity. Population-based studies of NAS going beyond Medicaid populations and hospital discharge data (HDD) alone are limited. Using statewide Tennessee (TN) HDD and birth certificate (BC) data, we examined trends and evaluated maternal and infant factors associated with NAS. We conducted a population-based descriptive study during 2013–2017 in TN. NAS infants were identified with International Classification of Diseases (ICD)-9-Clinical Modification (CM) and ICD-10-CM codes in HDD and linked to BC data using iterative deterministic matching algorithms. Descriptive analyses were conducted for infant and maternal factors (exposures) by NAS (outcome). Multivariable logistic regression models were used to estimate adjusted ORs and 95% CIs. NAS incidence increased from 13.4 to 15.4 per 1,000 live births between 2013 and 2017 (15% increase; ptrend<0.001), but remained stable in 2017. In adjusted models, maternal factors associated with reduced odds of NAS included breastfeeding (OR:0.55, 95%CI:0.52–0.59) and prenatal care (OR:0.36, 95%CI:0.32–0.41). Smoking, preterm birth, and lower birthweight were associated with increased odds of NAS. This study highlights the value of utilizing surveillance data to monitor trends and correlates of NAS to inform prevention efforts and targeting of public health resources.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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