Use of full automated microfluidic technique for determination of Zinc (II) in pharmaceutical preparations with 8-Hydroxyquinoline.

The full automated microfluidic system has been designed for the determination of zinc (II) ion in pharmaceutical samples home-made. Two-channel microchips (30 μl×4 cm) was designed in this study. The proposed system was controlled by using Arduino UNO and Mega microcontrollers. The first type was u...

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Publicado en:Journal of Basrah Researches (Sciences) Vol. 48; no. 2; pp. 14 - 27
Autores principales: Mkashaf, Ihsan A., Al-Sowdani, Kamel H., Aldarwish, Abdulla J. Y.
Formato: Artículo
Publicado: Republic of Iraq Ministry of Higher Education & Scientific Research (MOHESR) 2022
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Use of full automated microfluidic technique for determination of Zinc (II) in pharmaceutical preparations with 8-Hydroxyquinoline.
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          Mkashaf, Ihsan A.
          Al-Sowdani, Kamel H.
          Aldarwish, Abdulla J. Y.
        affil:
          Department of Chemistry, College of Education for Pure Science, University of Basrah, Basrah, Iraq.
          Department of Computer Science, College of Education for Pure Science, University of Basrah, Basrah, Iraq.
      su:
        Drugs
        Zinc
        Chemical reagents
        Detection limit
        Integrated circuits
        Electronic spreadsheets
      sug:
        subj:
          Drugs
          Zinc
          Chemical reagents
          Detection limit
          Integrated circuits
          Electronic spreadsheets
      keyword:
        الزنك الثنائي في المستحضرات الصيدالنية
        كاشف -8هيدروكسي كوينولين
        نظام مايكروفلودك محلي الصنع
        8-Hydroxyquinoline reagent
        Full automated microfluidic homemade
        Zinc(II) in pharmaceutical preparations
        الزنك الثنائي في المستحضرات الصيدالنية
        كاشف -8هيدروكسي كوينولين
        نظام مايكروفلودك محلي الصنع
      ab: The full automated microfluidic system has been designed for the determination of zinc (II) ion in pharmaceutical samples home-made. Two-channel microchips (30 μl×4 cm) was designed in this study. The proposed system was controlled by using Arduino UNO and Mega microcontrollers. The first type was utilized to control the homemade micro-peristaltic pump to withdraw samples and chemical reagents in the microchip and then to the spectrophotometer equipment with 7-microliter flow cell. The other one type is Mega, was used as a data-logger to manipulate and recording the results as peak height corresponding the concentration by using Microsoft Excel 2016 program. The linearity was ranged 1-7 µg/ml, the correlation coefficient (R2) was 0.9998. The relative standard deviation for ten measurements of Zn(II) ion 4 µg/ml was (0.982%), as well as the detection limit was 0.125 µg/ml. The dilution factor of this system was 1.07
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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