A comparison of passive and active dust sampling methods for measuring airborne methicillin-resistant Staphylococcus aureus in pig farms.

Methicillin-resistant strains of Staphylococcus aureus (MRSA) are resistant to most β-lactam antibiotics. Pigs are an important reservoir of livestock-associated MRSA (LA-MRSA), which is genetically distinct from both hospital and community-acquired MRSA. Occupational exposure to pigs on farms can l...

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Publicado en:Annals of Work Exposures & Health Vol. 67; no. 8; pp. 1004 - 1011
Autores principales: Rittscher, Anne E, Vlasblom, Abel A, Duim, Birgitta, Scherpenisse, Peter, Schothorst, Isabella J van, Wouters, Inge M, Gompel, Liese Van, Smit, Lidwien A M
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2023
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      pub: Oxford University Press / USA
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        10.1093/annweh/wxad033
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        atl: A comparison of passive and active dust sampling methods for measuring airborne methicillin-resistant Staphylococcus aureus in pig farms.
      aug:
        au:
          Rittscher, Anne E
          Vlasblom, Abel A
          Duim, Birgitta
          Scherpenisse, Peter
          Schothorst, Isabella J van
          Wouters, Inge M
          Gompel, Liese Van
          Smit, Lidwien A M
        affil: Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University , Yalelaan 2, 3584 CM Utrecht , The Netherlands
      sug:
        subj:
          Swine
          Agriculture
          Dust Analysis
          Methicillin-Resistant Staphylococcus Aureus
          Air Microbiology
          Air Analysis
          Human
          Occupational Exposure
          Inhalation Exposure
          Comparative Studies
          Netherlands
          Polymerase Chain Reaction Methods
          RNA
          Pearson's Correlation Coefficient
          Staphylococcal Infections Transmission
          Funding Source
      ab: Methicillin-resistant strains of Staphylococcus aureus (MRSA) are resistant to most β-lactam antibiotics. Pigs are an important reservoir of livestock-associated MRSA (LA-MRSA), which is genetically distinct from both hospital and community-acquired MRSA. Occupational exposure to pigs on farms can lead to LA-MRSA carriage by workers. There is a growing body of research on MRSA found in the farm environment, the airborne route of transmission, and its implication on human health. This study aims to directly compare two sampling methods used to measure airborne MRSA in the farm environment; passive dust sampling with electrostatic dust fall collectors (EDCs), and active inhalable dust sampling using stationary air pumps with Gesamtstaubprobenahme (GSP) sampling heads containing Teflon filters. Paired dust samples using EDCs and GSP samplers, totaling 87 samples, were taken from 7 Dutch pig farms, in multiple compartments housing pigs of varying ages. Total nucleic acids of both types of dust samples were extracted and targets indicating MRSA (femA, nuc, mecA) and total bacterial count (16S rRNA) were quantified using quantitative real-time PCRs. MRSA could be measured from all GSP samples and in 94% of the EDCs, additionally MRSA was present on every farm sampled. There was a strong positive relationship between the paired MRSA levels found in EDCs and those measured on filters (Normalized by 16S rRNA; Pearson's correlation coefficient r = 0.94, Not Normalized; Pearson's correlation coefficient r = 0.84). This study suggests that EDCs can be used as an affordable and easily standardized method for quantifying airborne MRSA levels in the pig farm setting.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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