Optimising the management of children with concomitant bladder dysfunction and behavioural disorders.

Bladder dysfunction and behavioural disorders in children are commonly concomitant; hence, it is difficult to treat each in isolation. Pharmacotherapy is common treatment for behavioural disorders, and these medications may have intended or unintended positive or negative bladder sequelae. This revi...

Descripción completa

Detalles Bibliográficos
Publicado en:European Child & Adolescent Psychiatry Vol. 32; no. 10; pp. 1989 - 2000
Autores principales: Eliezer, Dilharan D., Lam, Christopher, Smith, Angela, Coomarasamy, John Mithran, Samnakay, Naeem, Starkey, Malcolm R., Deshpande, Aniruddh V.
Formato: research systematic review tables/charts Journal Article
Publicado: Springer Nature Oct2023
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=172360629&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 172360629
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        10188827
        EJ3
      jtl: European Child & Adolescent Psychiatry
      issn: 10188827
      maglogo: N
    pubinfo:
      dt: Oct2023
      vid: 32
      iid: 10
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        172360629
        157710998
        172360629
        172360629
        10.1007/s00787-022-02016-4
        172360629
      ppf: 1989
      ppct: 11
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Optimising the management of children with concomitant bladder dysfunction and behavioural disorders.
      aug:
        au:
          Eliezer, Dilharan D.
          Lam, Christopher
          Smith, Angela
          Coomarasamy, John Mithran
          Samnakay, Naeem
          Starkey, Malcolm R.
          Deshpande, Aniruddh V.
        affil: https://ror.org/048sjbt91 John Hunter Children's Hospital, New Lambton Heights, NSW, Australia
      sug:
        subj:
          Mental Disorders Drug Therapy
          Mental Disorders Complications
          Bladder, Neurogenic Drug Therapy
          Antipsychotic Agents Therapeutic Use
          Human
          Male
          Female
          Child, Preschool
          Child
          Adolescence
          Systematic Review
          Embase
          Medline
          PubMed
          Psycinfo
          Serotonin Uptake Inhibitors Therapeutic Use
          Decision Making
          Funding Source
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Adolescent: 13-18 years
          Male
          Female
      ab: Bladder dysfunction and behavioural disorders in children are commonly concomitant; hence, it is difficult to treat each in isolation. Pharmacotherapy is common treatment for behavioural disorders, and these medications may have intended or unintended positive or negative bladder sequelae. This review identifies the literature regarding the effects of behavioural pharmacotherapy on bladder functioning and possible bladder management strategies in children with concomitant behaviour and bladder disorders to enable clinicians to better manage both conditions. A PROSPERO registered PRISMA-guided review of three major databases was performed. After an initial scoping study revealed significant heterogeneity, a narrative approach was undertaken to discuss the results of all relevant cases relating to children being treated with pharmacotherapy for behaviour disorders and outcomes related to bladder function. Studies were screened to identify those that described effects of commonly prescribed medications in children with behavioural disorders such as stimulants, alpha 2 agonists, tricyclic antidepressants (TCA), serotonin and noradrenergic reuptake inhibitors (SNRI), selective serotonin reuptake inhibitors (SSRI) and antipsychotics, and the findings and implications were summarised. The review identified 46 studies relevant to behavioural pharmacotherapy and bladder function (stimulants (n = 9), alpha 2 agonists (n = 2), TCAs (n = 7), SNRIs (n = 8), SSRIs (n = 8) and antipsychotics (n = 6). Six studies focused specifically on bladder management in children with behavioural disorders with concurrent behavioural pharmacotherapy. This review identifies useful factors that may assist clinicians with predicting unintended bladder effects following initiation of behavioural pharmacotherapy to facilitate the best approach to the treatment of bladder dysfunction in children with behavioural disorders. With this evidence, we have provided a useful decision-making algorithm to aide clinicians in the management of these dual pathologies.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N