Long-Read Sequencing with Hierarchical Clustering for Antiretroviral Resistance Profiling of Mixed Human Immunodeficiency Virus Quasispecies.

BACKGROUND: HIV infections often develop drug resistance mutations (DRMs), which can increase the risk of virological failure. However, it has been difficult to determine if minor mutations occur in the same genome or in different virions using Sanger sequencing and short-read sequencing methods. Ox...

Full description

Bibliographic Details

Published in:	Clinical Chemistry Vol. 69; no. 10; pp. 1174 - 1186
Main Authors:	Ting-Leung Ng, Timothy, Junhao Su, Hiu-Yin Lao, Wui-Wang Lui, Chloe Toi-Mei Chan, Amy Wing-Sze Leung, Hoi-Ching Jim, Stephanie, Lam-Kwong Lee, Shehzad, Sheeba, King-Gee Tam, Kingsley, Siu-Sing Leung, Kenneth, Tang, Forrest, Wing-Cheong Yam, Ruibang Luo, Kit-Hang Siu, Gilman
Format:	Journal Article
Published:	Oxford University Press / USA Oct2023
Online Access:	View this record in EBSCOhost