Patients' experiences of completing patient‐reported outcomes in clinical trials: An interview study.

This study aimed to gain insight into how older men diagnosed with prostate cancer experience responding to ePRO about their quality of life in a clinical trial as well as what motivates and demotivates them in the process. Drop‐outs in patient‐reported outcome studies are a well‐known challenge tha...

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Publicado en:International Journal of Urological Nursing Vol. 17; no. 3; pp. 180 - 188
Autores principales: Østergaard, Louise Dorner, Nørgaard, Birgitte, Holm, Malene Eiberg, Hansen, Ann‐Kirstine, Lund, Lars, Poulsen, Mads Hvid
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/ijun.12363
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        atl: Patients' experiences of completing patient‐reported outcomes in clinical trials: An interview study.
      aug:
        au:
          Østergaard, Louise Dorner
          Nørgaard, Birgitte
          Holm, Malene Eiberg
          Hansen, Ann‐Kirstine
          Lund, Lars
          Poulsen, Mads Hvid
        affil: Department of Urology, Odense University Hospital, Odense, Denmark
      sug:
        subj:
          Cancer Patients Psychosocial Factors
          Life Experiences
          Patient-Reported Outcomes
          Clinical Trials
          Research Dropouts
          Research Subject Retention
          Prostatic Neoplasms
          Quality of Life
          Human
          Aged
          Aged, 80 and Over
          Male
          Qualitative Studies
          Semi-Structured Interview
          Audiorecording
          Thematic Analysis
          Checklists
          Exploratory Research
          Prospective Studies
          Prostate-Specific Antigen
          Scales
          Clinical Assessment Tools
          Questionnaires
          Aged: 65+ years
          Aged, 80 & over
          Male
      ab: This study aimed to gain insight into how older men diagnosed with prostate cancer experience responding to ePRO about their quality of life in a clinical trial as well as what motivates and demotivates them in the process. Drop‐outs in patient‐reported outcome studies are a well‐known challenge that influence both the reliability and validity of clinical trials. Furthermore, retaining older people in electronic patient‐reported outcome (ePRO) studies has proven difficult. This study was based on qualitative semi‐structured interviews with 13 male patients. The interviews were conducted between April and May 2022 and were audio‐recorded and transcribed verbatim. We analysed the interview inductively using Braun and Clark's thematic analysis. Resulting in five core themes among participants' responses: (1) the ePRO frame is feasible, (2) it is challenging to rate one's life on a scale, (3) increased disease insight, (4) unmet expectations of emotional support, and (5) from motivation to demotivation. The informants were motivated primarily by the idea of helping with new knowledge, but also because ePRO was seen as easy to use and access from home. They were further motivated by the new knowledge they gained through ePRO about symptoms and the possibility to follow their own progress. However, relating to their own quality of life creates an expectation that nurses and doctors will do the same in their treatment, and when this does not happen, the initial motivation turns into demotivation as ePRO knowledge was not used to tailor their treatment and follow‐up. In conclusion, older men can participate in ePRO. They are motivated by helping with new knowledge, the ability to answer ePRO from home, and the insights they gain from the questionnaire. They lose motivation when their responses are not used to tailor their disease management.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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