Endoscopic causes and characteristics of missed gastric cancers after endoscopic submucosal dissection.

Because endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) preserves the entire stomach, missed gastric cancers (MGCs) are often found in the remaining gastric mucosa. However, the endoscopic causes of MGCs remain unclear. Therefore, we aimed to elucidate the endoscopic causes and...

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Publicado en:Gastrointestinal Endoscopy Vol. 98; no. 5; pp. 735 - 736
Autores principales: Shimada, Seitaro, Yabuuchi, Yohei, Kawata, Noboru, Maeda, Yuki, Yoshida, Masao, Yamamoto, Yoichi, Minamide, Tatsunori, Shigeta, Kohei, Takada, Kazunori, Kishida, Yoshihiro, Ito, Sayo, Imai, Kenichiro, Hotta, Kinichi, Ishiwatari, Hirotoshi, Matsubayashi, Hiroyuki, Ono, Hiroyuki
Formato: research Journal Article
Publicado: Elsevier B.V. Nov2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2023
      vid: 98
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      pub: Elsevier B.V.
      place: New York, New York
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        10.1016/j.gie.2023.02.024
        173050872
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        atl: Endoscopic causes and characteristics of missed gastric cancers after endoscopic submucosal dissection.
      aug:
        au:
          Shimada, Seitaro
          Yabuuchi, Yohei
          Kawata, Noboru
          Maeda, Yuki
          Yoshida, Masao
          Yamamoto, Yoichi
          Minamide, Tatsunori
          Shigeta, Kohei
          Takada, Kazunori
          Kishida, Yoshihiro
          Ito, Sayo
          Imai, Kenichiro
          Hotta, Kinichi
          Ishiwatari, Hirotoshi
          Matsubayashi, Hiroyuki
          Ono, Hiroyuki
        affil: Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan
      sug:
        subj:
          Endoscopy, Gastrointestinal
          Stomach Neoplasms Diagnosis
          Failure to Diagnose
          Gastric Mucosa Surgery
          Stomach Neoplasms Surgery
          Intraoperative Monitoring
          Human
          Retrospective Design
          Record Review
          Cancer Patients
          Logistic Regression
          Surgical Patients
          Descriptive Statistics
          Odds Ratio
          Confidence Intervals
          Stomach Pathology
          Pyloric Antrum Pathology
      ab: Because endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) preserves the entire stomach, missed gastric cancers (MGCs) are often found in the remaining gastric mucosa. However, the endoscopic causes of MGCs remain unclear. Therefore, we aimed to elucidate the endoscopic causes and characteristics of MGCs after ESD. From January 2009 to December 2018, all patients undergoing ESD for initially detected EGC were enrolled. According to a review of EGD images before ESD, we identified the endoscopic causes (perceptual, exposure, sampling errors, and inadequate preparation) and characteristics of MGC in each endoscopic cause. Of 2208 patients who underwent ESD for initial EGC, 82 patients (3.7%) had 100 MGCs. The breakdown of endoscopic causes of MGCs was as follows: 69 (69%) perceptual errors, 23 (23%) exposure errors, 7 (7%) sampling errors, and 1 (1%) inadequate preparation. Logistic regression analysis showed that the risk factors for perceptual error were male sex (odds ratio [OR], 2.45; 95% confidence interval [CI], 1.16-5.18), isochromatic coloration (OR, 3.17; 95% CI, 1.47-6.84), greater curvature (OR, 2.31; 95% CI, 1.121-4.40), and lesion size ≤12 mm (OR, 1.74; 95% CI, 1.07-2.84). The sites of exposure errors were around the incisura angularis (11 [48%]), posterior wall of the gastric body (6 [26%]), and antrum (5 [21%]). We identified MGCs in 4 categories and clarified their characteristics. Quality improvements in EGD observation, with attention to the risks of perceptual and site of exposure errors, can potentially prevent missing EGCs.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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