Electronic Antiretroviral Therapy Adherence Monitors and Associated Interventions Improve Adolescent–Caregiver Relationships and Self-Efficacy Among Adolescents and Young Adults with HIV in Uganda.
Many adolescents and young adults with HIV (AYWH) struggle with antiretroviral therapy (ART) adherence and experience poorer outcomes than adults. Relevant factors include forgetfulness and poor self-efficacy related to their evolving neurobiology. We qualitatively explored experiences of AYWH–careg...
| Publicado en: | AIDS Patient Care & STDs Vol. 37; no. 10; pp. 489 - 495 |
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| Autores principales: | , , , , , , , , |
| Formato: | clinical trial research Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Oct2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=173113266&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 173113266 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10872914 33C jtl: AIDS Patient Care & STDs issn: 10872914 maglogo: N pubinfo: dt: Oct2023 vid: 37 iid: 10 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 173113266 173113266 173113266 10.1089/apc.2023.0164 173113266 ppf: 489 ppct: 6 formats: tig: atl: Electronic Antiretroviral Therapy Adherence Monitors and Associated Interventions Improve Adolescent–Caregiver Relationships and Self-Efficacy Among Adolescents and Young Adults with HIV in Uganda. aug: au: Adong, Julian Asiimwe, Stephen Nansera, Denis Muyindike, Winnie Tumuhairwe, John B. Baijuka, Robert Tindimwebwa, Edna Garrison, Lindsey E. Haberer, Jessica E. affil: Mbarara University of Science and Technology, Departments of Pediatrics and Internal Medicine, Faculty of Medicine, Mbarara, Uganda. sug: subj: HIV-Positive Persons In Adolescence Caregivers Interpersonal Relations Evaluation Self-Efficacy In Adolescence Medication Compliance Evaluation Anti-Retroviral Agents Therapeutic Use HIV Infections Drug Therapy Treatment Outcomes Human Qualitative Studies Clinical Trials Uganda Male Female Adolescence Young Adult Adult Interviews Content Analysis Descriptive Statistics Implementation Science Drug Monitoring Funding Source Adolescent: 13-18 years Adult: 19-44 years Male Female ab: Many adolescents and young adults with HIV (AYWH) struggle with antiretroviral therapy (ART) adherence and experience poorer outcomes than adults. Relevant factors include forgetfulness and poor self-efficacy related to their evolving neurobiology. We qualitatively explored experiences of AYWH–caregivers dyads using real-time ART adherence monitors and associated reminder functions in the home setting. As part of an implementation science-oriented study, AYWH used the Wisepill adherence monitor for 3 months. AYWH could also opt for short message service (SMS) self-reminders, a self-selected social supporter for delayed or missed doses, or an alarm reminder. We conducted in-depth interviews with randomly selected AYWH–caregiver dyads regarding their experience using the monitor. Qualitative data were analyzed using inductive content analysis. We completed 15 AYWH–caregiver dyad interviews. Of the AYWH, 67% were female, mean age was 16 years, 56% lived with their biological mother, and 86% were virologically suppressed. AYWH and their caregivers generally found the adherence monitors acceptable, though some had privacy concerns. AYWH felt the monitors helped them take charge of their medication, largely through the real-time alarm and SMS reminders; this took the burden of adherence reminders away from the caregivers, improving strained AYWH–caregiver relationships. Two adolescents reported rebound poor adherence after monitor withdrawal. ART adherence monitors and associated tools were largely acceptable to AYWH and their caregivers in home settings. The intervention helped improve AYWH self-efficacy and alleviated burden from some AYWH–caregiver relationships. Rebound poor adherence suggests the need for on-going support and/or other means to achieve intrinsic mechanisms for sustained adherence. Clinical Trial Registration number: NCT03825952. pubtype: Academic Journal doctype: clinical trial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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