Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults.

Objective: Previous research has primarily focused on the association between muscle strength and global cognitive function in older adults, while the connection between muscle strength and advanced cognitive function such as inhibition and working memory (WM) remains unclear. This study aimed to in...

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Publicado en:Frontiers in Aging Neuroscience pp. 1 - 13
Autores principales: Zhidong Cai, Xing Wang, Qiang Wang
Formato: pictorial research tables/charts Journal Article
Publicado: Frontiers Media S.A. 2023
Acceso en línea:Ver este registro en EBSCOhost
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        16634365
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      jtl: Frontiers in Aging Neuroscience
      issn: 16634365
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      dt: 2023
      pid: 40038
      pub: Frontiers Media S.A.
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        173135782
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        10.3389/fnagi.2023.1243283
        173135782
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        atl: Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults.
      aug:
        au:
          Zhidong Cai
          Xing Wang
          Qiang Wang
        affil: Department of Physical Education, Suzhou University of Science and Technology, Suzhou, China
      sug:
        subj:
          Muscle Strength Evaluation
          Memory, Short Term Evaluation
          Cognition Evaluation
          Task Performance and Analysis In Old Age
          Prefrontal Cortex Physiology
          Hemodynamics In Old Age
          Human
          Cross Sectional Studies
          Spectroscopy, Near-Infrared Methods
          Grip Strength
          Lower Extremity Physiology
          Reaction Time
          China
          Aged
          Aged, 80 and Over
          Male
          Female
          Funding Source
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Objective: Previous research has primarily focused on the association between muscle strength and global cognitive function in older adults, while the connection between muscle strength and advanced cognitive function such as inhibition and working memory (WM) remains unclear. This study aimed to investigate the relationship among muscle strength, WM, and task-related cortex hemodynamics. Methods: We recruited eighty-one older adults. Muscle strength was measured using a grip and lower limb strength protocol. We measured the WM performance by using reaction time (RT) and accuracy (ACC) in the N-back task and the cortical hemodynamics of the prefrontal cortex (PFC) by functional near-infrared spectroscopy (fNIRS). Results: We found positive correlations between grip strength (p < 0.05), 30-s sit-up (p < 0.05) and ACC, negative correlation between grip strength (p < 0.05) and RT. Furthermore, we observed positive correlations between grip strength and the level of oxygenated hemoglobin (HbO2) in dorsolateral prefrontal cortex, frontopolar area, ventrolateral prefrontal cortex (p < 0.05), and negative correlations between grip strength and the level of deoxygenated hemoglobin (Hb) in left dorsolateral prefrontal cortex, frontopolar area, left ventrolateral prefrontal cortex (p < 0.05). Additionally, we noticed positive correlations between RT and the level of Hb in left dorsolateral prefrontal cortex, right frontopolar area (p < 0.05), and negative correlations between RT and the level of HbO2 in left dorsolateral prefrontal cortex, frontopolar area (p < 0.05). However, the cortical hemodynamics did not mediate the relationship between muscle strength and WM performance (RT, ACC). Conclusion: The grip strength of older adults predicted WM in the cross-section study. The level of hemodynamics in PFC can serve as a predictor of WM.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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