International Clinical Research Data Ecosystem: From Data Standardization to Federated Analysis...European Federation for Medical Informatics (EFMI) Special Topic Conference, October 25-27, 2023, Turin, Italy.

Within the HORIZON 2020 project ORCHESTRA, patient data from numerous clinical studies in Europe related to COVID-19 were harmonized to create new knowledge on the disease. In this article, we describe the ecosystem that was established for the management of data collected and contributed by project...

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Publicado en:Studies in Health Technology & Informatics Vol. 309; pp. 133 - 135
Autores principales: RINALDI, Eugenia, DELLACASA, Chiara, PUSKARIC, Miroslav, OSMO, Thomas, GORSKA, Anna, STELLMACH, Caroline
Formato: proceedings research Journal Article
Publicado: Sage Publications Inc. 2023
Acceso en línea:Ver este registro en EBSCOhost
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        atl: International Clinical Research Data Ecosystem: From Data Standardization to Federated Analysis...European Federation for Medical Informatics (EFMI) Special Topic Conference, October 25-27, 2023, Turin, Italy.
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        au:
          RINALDI, Eugenia
          DELLACASA, Chiara
          PUSKARIC, Miroslav
          OSMO, Thomas
          GORSKA, Anna
          STELLMACH, Caroline
        affil: Berlin Institute of Health at Charité-Universitaetsmedizin Berlin, Germany
      sug:
        subj:
          Clinical Research
          Data Management
          Data Analysis
          Congresses and Conferences Italy
          Italy
          Human
          Research Protocols
          Information Storage
          Information Retrieval
          Nomenclature
      ab: Within the HORIZON 2020 project ORCHESTRA, patient data from numerous clinical studies in Europe related to COVID-19 were harmonized to create new knowledge on the disease. In this article, we describe the ecosystem that was established for the management of data collected and contributed by project partners. Study protocols elements were mapped to interoperability standards to establish a common terminology. That served as the basis of identifying common concepts used across several studies. Harmonized data were used to perform analysis directly on a central database and also through federated analysis when data was not permitted to leave the local server(s). This ecosystem facilitates the answering of research questions and generation of new knowledge available for the scientific community.
      pubtype: Academic Journal
      doctype:
        proceedings
        research
        Journal Article
      ougenre: Article
    language: English
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