Vitamin D and Metabolic Syndrome in Working Age Subjects from an Obesity Clinic.

Serum vitamin D (VitD) levels have been inversely related with metabolic syndrome (MetS), although the direct impact of VitD is still debated. This study examined 879 subjects of working age from an obesity and occupational clinic in Milan, Italy. Among these participants, 316 had MetS, while 563 di...

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Publicado en:Nutrients Vol. 15; no. 20; pp. 4354 - 4365
Autores principales: Vigna, Luisella, Speciani, Michela Carola, Tirelli, Amedea Silvia, Bravi, Francesca, La Vecchia, Carlo, Conte, Caterina, Gori, Francesca
Formato: research tables/charts Journal Article
Publicado: MDPI Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2023
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      pub: MDPI
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        atl: Vitamin D and Metabolic Syndrome in Working Age Subjects from an Obesity Clinic.
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        au:
          Vigna, Luisella
          Speciani, Michela Carola
          Tirelli, Amedea Silvia
          Bravi, Francesca
          La Vecchia, Carlo
          Conte, Caterina
          Gori, Francesca
        affil: Centro Obesità e Lavoro, Unità di Salute Occupazionale, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy
      sug:
        subj:
          Vitamin D Blood
          Vitamins
          Metabolic Syndrome X
          Obesity
          Primary Health Care Italy
          Occupational Health
          Vitamin D Deficiency Complications
          Human
          Male
          Female
          Adolescence
          Young Adult
          Adult
          Middle Age
          Italy
          Multiple Logistic Regression
          Body Mass Index
          Risk Assessment
          Exercise
          Leisure Activities
          Descriptive Statistics
          Comparative Studies
          Odds Ratio
          Confidence Intervals
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Serum vitamin D (VitD) levels have been inversely related with metabolic syndrome (MetS), although the direct impact of VitD is still debated. This study examined 879 subjects of working age from an obesity and occupational clinic in Milan, Italy. Among these participants, 316 had MetS, while 563 did not. A multiple logistic regression analysis was conducted to determine the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) for MetS in relation to serum VitD levels. After controlling for age, sex, leisure time physical activity, and body mass index (BMI), individuals with VitD levels between 20 and 29.9 ng/dL, or at least 30 ng/dL, had approximately half the risk of developing MetS (OR: 0.52, 95% CI: 0.32–0.86 and OR: 0.50, 95% CI: 0.25–0.99, respectively) compared to those with VitD levels below 10 ng/dL. This study presents further evidence of the beneficial effect of adequate VitD levels on the risk of MetS in a population of overweight/obese workers, even after adjusting for BMI. This study supports the importance of testing for and—if required—supplementing VitD in individuals with metabolic risk factors.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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