Healthcare costs and use before and after opioid overdose in Veterans Health Administration patients with opioid use disorder.

Aims: To compare healthcare costs and use between United States (US) Veterans Health Administration (VHA) patients with opioid use disorder (OUD) who experienced an opioid overdose (OD cohort) and patients with OUD who did not experience an opioid overdose (non-OD cohort). Design: This is a retrospe...

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Publicado en:Addiction Vol. 118; no. 11; pp. 2203 - 2215
Autores principales: Joyce, Vilija R., Oliva, Elizabeth M., Garcia, Carla C., Trafton, Jodie, Asch, Steven M., Wagner, Todd H., Humphreys, Keith, Owens, Douglas K., Bounthavong, Mark
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Healthcare costs and use before and after opioid overdose in Veterans Health Administration patients with opioid use disorder.
      aug:
        au:
          Joyce, Vilija R.
          Oliva, Elizabeth M.
          Garcia, Carla C.
          Trafton, Jodie
          Asch, Steven M.
          Wagner, Todd H.
          Humphreys, Keith
          Owens, Douglas K.
          Bounthavong, Mark
        affil: VA Health Economics Resource Center, US Department of Veterans Affairs, VA Palo Alto Health Care System, Palo Alto, CA, USA
      sug:
        subj:
          Health Care Costs
          Narcotics
          Substance Use Disorders
          Overdose
          Veterans Health Services
          Human
          Comparative Studies
          Retrospective Design
          Confidence Intervals
          Economics
          Patient Admission
          Descriptive Statistics
          Funding Source
      ab: Aims: To compare healthcare costs and use between United States (US) Veterans Health Administration (VHA) patients with opioid use disorder (OUD) who experienced an opioid overdose (OD cohort) and patients with OUD who did not experience an opioid overdose (non-OD cohort). Design: This is a retrospective cohort study of administrative and clinical data. Setting: The largest integrated national health-care system is the US Veterans Health Administration's healthcare systems. Participants: We included VHA patients diagnosed with OUD from October 1, 2017 through September 30, 2018. We identified the index date of overdose for patients who had an overdose. Our control group, which included patients with OUD who did not have an overdose, was randomly assigned an index date. A total of 66 513 patients with OUD were included for analysis (OD cohort: n = 1413; non-OD cohort: n = 65 100). Measurements: Monthly adjusted healthcare-related costs and use in the year before and after the index date. We used generalized estimating equation models to compare patients with an opioid overdose and controls in a difference-in-differences framework. Findings: Compared with the non-OD cohort, an opioid overdose was associated with an increase of $16 890 [95% confidence interval (CI) = $15 611--18 169; P < 0.001] in healthcare costs for an estimated $23.9 million in direct costs to VHA (95% CI = $22.1 million, $25.7 million) within the 30 days following overdose after adjusting for baseline characteristics. Inpatient costs ($13 515; 95% CI = $12 378-14 652; P < 0.001) reflected most of this increase. Inpatient days (+6.15 days; 95% CI, = 5.33-6.97; P < 0.001), inpatient admissions (+1.01 admissions; 95% CI = 0.93-1.10; P < 0.001) and outpatient visits (+1.59 visits; 95% CI = 1.34-1.84; P < 0.001) also increased in the month after opioid overdose. Within the overdose cohort, healthcare costs and use remained higher in the year after overdose compared with pre-overdose trends. Conclusions: The US Veterans Health Administration patients with opioid use disorder (OUD) who have experienced an opioid overdose have increased healthcare costs and use that remain significantly higher in the month and continuing through the year after overdose than OUD patients who have not experienced an overdose.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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