Motivational interviewing and problem-solving therapy intervention for patients on antiretroviral therapy for HIV in Tshwane, South Africa: A randomized controlled trial to assess the impact on alcohol consumption.
Background and Aims: Reduction of alcohol consumption is important for people undergoing treatment for HIV. We tested the efficacy of a brief intervention for reducing the average volume of alcohol consumed among patients on HIV antiretroviral therapy (ART). Design, Setting and Participants: This st...
| Publicado en: | Addiction Vol. 118; no. 11; pp. 2164 - 2177 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research tables/charts randomized controlled trial Journal Article |
| Publicado: |
Wiley-Blackwell
Nov2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=173385893&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 173385893 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Nov2023 vid: 118 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 173385893 164408344 173385893 173385893 10.1111/add.16278 173385893 ppf: 2164 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Motivational interviewing and problem-solving therapy intervention for patients on antiretroviral therapy for HIV in Tshwane, South Africa: A randomized controlled trial to assess the impact on alcohol consumption. aug: au: Parry, Charles D. H. Myers, Bronwyn Londani, Mukhethwa Shuper, Paul A. van Rensburg, Charl Janse Manda, Samuel O. M. Nkosi, Sebenzile Kekwaletswe, Connie T. Hahn, Judith A. Rehm, Jürgen Sorsdahl, Katherine Morojele, Neo K. affil: Alcohol, Tobacco and Other Drug Research Unit, South African Medical Research Council, Cape Town, South Africa sug: subj: HIV Infections Drug Therapy Anti-Retroviral Agents Therapeutic Use Alcoholic Beverages Adverse Effects Alcohol Drinking Prevention and Control Patient Education Methods Motivational Interviewing Problem Solving Outcomes of Education Human South Africa Multicenter Studies Randomized Controlled Trials Random Assignment Adult Middle Age Male Female Confidence Intervals Descriptive Statistics Comparative Studies Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background and Aims: Reduction of alcohol consumption is important for people undergoing treatment for HIV. We tested the efficacy of a brief intervention for reducing the average volume of alcohol consumed among patients on HIV antiretroviral therapy (ART). Design, Setting and Participants: This study used a two-arm multi-centre randomized controlled trial with follow-up to 6 months. Recruitment occurred between May 2016 and October 2017 at six ART clinics at public hospitals in Tshwane, South Africa. Participants were people living with HIV, mean age 40.8 years [standard deviation (SD) = 9.07], 57.5% female, and on average 6.9 years (SD = 3.62) on ART. At baseline (BL), the mean number of drinks consumed over the past 30 days was 25.2 (SD = 38.3). Of 756 eligible patients, 623 were enrolled. Intervention: Participants were randomly assigned to a motivational interviewing (MI)/ problem-solving therapy (PST) intervention arm (four modules of MI and PST delivered over two sessions by interventionists) or a treatment as usual (TAU) comparison arm. People assessing outcomes were masked to group assignment. Measurements: The primary outcome was the number of standard drinks (15 ml pure alcohol) consumed during the past 30 days assessed at 6-month follow-up (6MFU). Findings: Of the 305 participants randomized to MI/PST, 225 (74%) completed the intervention (all modules). At 6MFU, retention was 88% for the control and 83% for the intervention arm. In support of the hypothesis, an intention-to-treat-analysis for the primary outcome at 6MFU was -0.410 (95% confidence interval = -0.670 to -0.149) units lower on log scale in the intervention group than in the control group (P = 0.002), a 34% relative reduction in the number of drinks. Sensitivity analyses were undertaken for patients who had alcohol use disorders identification test (AUDIT) scores ≥8 at BL (n = 299). Findings were similar to those of the whole sample. Conclusions: In South Africa, a motivational interviewing/problem-solving therapy intervention significantly reduced drinking levels in HIV-infected patients on antiretroviral therapy at 6-month follow-up. pubtype: Academic Journal doctype: research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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