Investigating the Influence of Autism Spectrum Traits on Face Processing Mechanisms in Developmental Prosopagnosia.

Autism traits are common exclusionary criteria in developmental prosopagnosia (DP) studies. We investigated whether autism traits produce qualitatively different face processing in 43 DPs with high vs. low autism quotient (AQ) scores. Compared to controls (n = 27), face memory and perception were si...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 53; no. 12; pp. 4787 - 4809
Autores principales: Fry, Regan, Li, Xian, Evans, Travis C., Esterman, Michael, Tanaka, James, DeGutis, Joseph
Formato: research tables/charts Journal Article
Publicado: Springer Nature Dec2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2023
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      pub: Springer Nature
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        atl: Investigating the Influence of Autism Spectrum Traits on Face Processing Mechanisms in Developmental Prosopagnosia.
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        au:
          Fry, Regan
          Li, Xian
          Evans, Travis C.
          Esterman, Michael
          Tanaka, James
          DeGutis, Joseph
        affil: https://ror.org/04v00sg98 Boston Attention and Learning Laboratory, VA Boston Healthcare System, 150 S. Huntington Ave., 182JP, 02130, Boston, MA, USA
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        subj:
          Autism Spectrum Disorder Diagnosis
          Autism Spectrum Disorder Complications
          Face Perception Physiology
          Agnosia Rehabilitation
          Human
          Male
          Female
          Funding Source
          Emotions
          Phenotype
          Sample Size
          Analysis of Variance
          Male
          Female
      ab: Autism traits are common exclusionary criteria in developmental prosopagnosia (DP) studies. We investigated whether autism traits produce qualitatively different face processing in 43 DPs with high vs. low autism quotient (AQ) scores. Compared to controls (n = 27), face memory and perception were similarly deficient in the high- and low-AQ DPs, with the high-AQ DP group additionally showing deficient face emotion recognition. Task-based fMRI revealed reduced occipito-temporal face selectivity in both groups, with high-AQ DPs additionally demonstrating decreased posterior superior temporal sulcus selectivity. Resting-state fMRI showed similar reduced face-selective network connectivity in both DP groups compared with controls. Together, this demonstrates that high- and low-AQ DP groups have very similar face processing deficits, with additional facial emotion deficits in high-AQ DPs.
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    language: English
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