A Fusion-Based Machine Learning Approach for Autism Detection in Young Children Using Magnetoencephalography Signals.

In this study, we aimed to find biomarkers of autism in young children. We recorded magnetoencephalography (MEG) in thirty children (4–7 years) with autism and thirty age, gender-matched controls while they were watching cartoons. We focused on characterizing neural oscillations by amplitude (power...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 53; no. 12; pp. 4830 - 4849
Autores principales: Barik, Kasturi, Watanabe, Katsumi, Bhattacharya, Joydeep, Saha, Goutam
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Dec2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2023
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      pub: Springer Nature
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        atl: A Fusion-Based Machine Learning Approach for Autism Detection in Young Children Using Magnetoencephalography Signals.
      aug:
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          Barik, Kasturi
          Watanabe, Katsumi
          Bhattacharya, Joydeep
          Saha, Goutam
        affil: https://ror.org/03w5sq511 Department of Electronics and Electrical Communication Engineering, Indian Institute of Technology Kharagpur, Kharagpur, India
      sug:
        subj:
          Autism Spectrum Disorder Diagnosis
          Machine Learning Methods
          Electroencephalography Utilization
          Electromagnetic Fields Utilization
          Biological Markers
          Human
          Child, Preschool
          Child
          Sensitivity and Specificity
          Descriptive Statistics
          Autism Spectrum Disorder Physiopathology
          Diagnosis, Neurologic
          Child, Preschool: 2-5 years
          Child: 6-12 years
      ab: In this study, we aimed to find biomarkers of autism in young children. We recorded magnetoencephalography (MEG) in thirty children (4–7 years) with autism and thirty age, gender-matched controls while they were watching cartoons. We focused on characterizing neural oscillations by amplitude (power spectral density, PSD) and phase (preferred phase angle, PPA). Machine learning based classifier showed a higher classification accuracy (88%) for PPA features than PSD features (82%). Further, by a novel fusion method combining PSD and PPA features, we achieved an average classification accuracy of 94% and 98% for feature-level and score-level fusion, respectively. These findings reveal discriminatory patterns of neural oscillations of autism in young children and provide novel insight into autism pathophysiology.
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        research
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      ougenre: Article
    language: English
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