Heart failure classifications via non‐invasive pressure volume loops from echocardiography.

Background: Left ventricular pressure‐volume (LV‐PV) loops provide comprehensive characterization of cardiovascular system in both health and disease, which are the essential element of the hemodynamic evaluation of heart failure (HF). This study attempts to achieve more detailed HF classifications...

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Publicado en:Echocardiography Vol. 40; no. 11; pp. 1205 - 1216
Autores principales: Liu, Xiaoli, Chen, Xu, Xia, Shaoyan, Yang, Feifei, Zhu, Haogang, He, Kunlun
Formato: equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2023
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.15696
        173552334
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      tig:
        atl: Heart failure classifications via non‐invasive pressure volume loops from echocardiography.
      aug:
        au:
          Liu, Xiaoli
          Chen, Xu
          Xia, Shaoyan
          Yang, Feifei
          Zhu, Haogang
          He, Kunlun
        affil: The School of Biological Science and Medical Engineering, Beihang University, Beijing, China
      sug:
        subj:
          Heart Failure Classification
          Echocardiography
          Stroke Volume
          Human
          Ventricular Function, Left
          Heart Anatomy and Histology
          Machine Learning
          Ventricular Ejection Fraction
          Descriptive Statistics
          Funding Source
          Sensitivity and Specificity
      ab: Background: Left ventricular pressure‐volume (LV‐PV) loops provide comprehensive characterization of cardiovascular system in both health and disease, which are the essential element of the hemodynamic evaluation of heart failure (HF). This study attempts to achieve more detailed HF classifications by non‐invasive LV‐PV loops from echocardiography and analyzes contribution of parameters to HF classifications. Methods: Firstly, non‐invasive PV loops are established by time‐varying elastance model where LV volume curves were extracted from apical‐four‐chambers view of echocardiographic videos. Then, 16 parameters related to cardiac structure and functions are automatically acquired from PV loops. Next, we applied six machine learning (ML) methods to divide four categories. On this premise, we choose the best performing classifier among machine learning approaches for feature ranking. Finally, we compare the contributions of different parameters to HF classifications. Results: By the experimental, the PV loops were successfully acquired in 1076 cases. When single left ventricular ejection fraction (LVEF) is used for HF classifications, the accuracy of the model is 91.67%. When added parameters extracted from ML‐derived LV‐PV loops, the classification accuracy is 96.57%, which improved by 5.1%. Especially, our parameters have a great improvement in the classification of non‐HF controls and heart failure with preserved ejection fraction (HFpEF). Conclusions: We successfully presented the classification of HF by machine derived non‐invasive LV‐PV loops, which has the potential to improve the diagnosis and management of heart failure in clinic. Moreover, ventriculo‐arterial (VA) coupling and ventricular efficiency were demonstrated important factors for ML‐based HF classification model besides LVEF.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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