Targeted DNA Methylation Analysis Facilitates Leukocyte Counts in Dried Blood Samples.

BACKGROUND: Cell-type specific DNA methylation (DNAm) can be employed to determine the numbers of leukocyte subsets in blood. In contrast to conventional methods for leukocyte counts, which are based on cellular morphology or surface marker protein expression, the cellular deconvolution based on DNA...

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Bibliographic Details
Published in:Clinical Chemistry Vol. 69; no. 11; pp. 1283 - 1295
Main Authors: Hubens, Wouter H. G., Maié, Tiago, Schnitker, Matthis, Bocova, Ledio, Puri, Deepika, Wessiepe, Martina, Kramer, Jan, Rink, Lothar, Koschmieder, Steffen, Costa, Ivan G., Wagner, Wolfgang
Format: Journal Article
Published: Oxford University Press / USA Nov2023
Online Access:View this record in EBSCOhost