Combinatorial Effects of Transcutaneous Spinal Stimulation and Task-Specific Training to Enhance Hand Motor Output after Paralysis.

Despite the positive results in upper limb (UL) motor recovery after using electrical neuromodulation in individuals after cervical spinal cord injury (SCI) or stroke, there has been limited exploration of potential benefits of combining task-specific hand grip training with transcutaneous electrica...

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Publicado en:Topics in Spinal Cord Injury Rehabilitation Vol. 29; pp. 15 - 23
Autores principales: Oh, Jeonghoon, Scheffler, Michelle S., Mahan, Erin E., King, Shane T., Martin, Catherine A., Dinh, Jenny, Steele, Alexander G., O'Malley, Marcia K., Sayenko, Dimitry G.
Formato: clinical trial pictorial research tables/charts Journal Article
Publicado: KnowledgeWorks Global, Ltd 2023Suppl
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Combinatorial Effects of Transcutaneous Spinal Stimulation and Task-Specific Training to Enhance Hand Motor Output after Paralysis.
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        au:
          Oh, Jeonghoon
          Scheffler, Michelle S.
          Mahan, Erin E.
          King, Shane T.
          Martin, Catherine A.
          Dinh, Jenny
          Steele, Alexander G.
          O'Malley, Marcia K.
          Sayenko, Dimitry G.
        affil: Department of Neurosurgery, Center for Translational Neural Prosthetics and Interfaces, Center for Neuroregeneration, Houston Methodist Research Institute, Houston, Texas, USA
      sug:
        subj:
          Task Performance and Analysis
          Paralysis Rehabilitation
          Transcutaneous Electric Nerve Stimulation Methods
          Evoked Potentials, Motor Physiology
          Hand Physiology
          Training Effect (Physiology) Evaluation
          Noninvasive Procedures
          Grip Strength
          Human
          Funding Source
          Spinal Cord Injuries
          Stroke
          Dynamometry
          Electromyography
          Feedback
          Treatment Outcomes
          Clinical Trials
          Crossover Design
          Adult
          Middle Age
          Female
          Male
          Repeated Measures
          Analysis of Variance
          Kruskal-Wallis Test
          Pretest-Posttest Design
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Despite the positive results in upper limb (UL) motor recovery after using electrical neuromodulation in individuals after cervical spinal cord injury (SCI) or stroke, there has been limited exploration of potential benefits of combining task-specific hand grip training with transcutaneous electrical spinal stimulation (TSS) for individuals with UL paralysis. This study investigates the combinatorial effects of task-specific hand grip training and noninvasive TSS to enhance hand motor output after paralysis. Four participants with cervical SCI classified as AIS A and B and two participants with cerebral stroke were recruited in this study. The effects of cervical TSS without grip training and during training with sham stimulation were contrasted with hand grip training with TSS. TSS was applied at midline over cervical spinal cord. During hand grip training, 5 to 10 seconds of voluntary contraction were repeated at a submaximum strength for approximately 10 minutes, three days per week for 4 weeks. Signals from hand grip dynamometer along with the electromyography (EMG) activity from UL muscles were recorded and displayed as visual feedback. Our case study series demonstrated that combined task-specific hand grip training and cervical TSS targeting the motor pools of distal muscles in the UL resulted in significant improvements in maximum hand grip strength. However, TSS alone or hand grip training alone showed limited effectiveness in improving grip strength. Task-specific hand grip training combined with TSS can result in restoration of hand motor function in paralyzed upper limbs in individuals with cervical SCI and stroke.
      pubtype: Academic Journal
      doctype:
        clinical trial
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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