| Sumario: | Background: Hypertension is characterized by abnormally high arterial blood pressure and is a public health problem with a high prevalence of 20%-30% worldwide. This research combined multiple logistic regression (MLR) and multilayer feedforward neural networks to construct and validate a model for evaluating the factors linked with hypertension in patients with dyslipidemia. Methods: A total of 1000 data entries from Hospital Universiti Sains Malaysia and advanced computational statistical modeling methodologies were used to evaluate seven traits associated with hypertension. R-Studio software was utilized. Each sample's statistics were calculated using a hybrid model that included bootstrapping. Results: Variable validation was performed by using the well-established bootstrap-integrated MLR technique. All variables affected the hazard ratio as follows: total cholesterol (ß1: -0.00664; p < 0.25), diabetes status (ß2: 0.62332; p < 0.25), diastolic reading (ß3: 0.08160; p < 0.25), height measurement (ß4: -0.05411; p < 0.25), coronary heart disease incidence (ß5: 1.42544; p < 0.25), triglyceride reading (ß6: 0.00616; p < 0.25), and waist reading (ß7: -0.00158; p < 0.25). Conclusions: A hybrid approach was developed and extensively tested. The hybrid technique is superior to other standalone techniques and allows an improved understanding of the influence of variables on outcomes.
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