Correlation between retinal nerve fiber layer thickness and cognitive function in patients with mild ischemic stroke.

Objective To investigate the association between retinal nerve fiber layer (RNFL) thickness and cognitive dysfunction in patients with mild ischemic stroke. Methods Total 146 patients with mild ischemic stroke that diagnosed and treated in Chengde Central Hospital in Hebei from January 2020 to Decem...

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Publicado en:Chinese Journal of Contemporary Neurology & Neurosurgery Vol. 23; no. 11; pp. 1001 - 1010
Autores principales: YANG Fei, PEI Cun-wen, LIU Jing-hua, ZHANG Ying, ZHENG Yi, ZHANG Jiang-tao, CUI Xiu-ying
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Chinese Journal of Contemporary Neurology & Neurosurgery Nov2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2023
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      pub: Chinese Journal of Contemporary Neurology & Neurosurgery
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        10.3969/j.issn.1672-6731.2023.11.008
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        atl: Correlation between retinal nerve fiber layer thickness and cognitive function in patients with mild ischemic stroke.
      aug:
        au:
          YANG Fei
          PEI Cun-wen
          LIU Jing-hua
          ZHANG Ying
          ZHENG Yi
          ZHANG Jiang-tao
          CUI Xiu-ying
        affil: Grade 2021, Graduate School of Chengde Medical University, Chengde 067000, Hebei, China
      sug:
        subj:
          Ischemic Stroke Complications
          Retina Innervation
          Optic Nerve Radiography
          Nerve Fibers Radiography
          Cognition Evaluation
          Cognition Disorders Risk Factors
          Tomography, Optical Coherence
          Risk Assessment
          Human
          Stroke Patients
          China
          Nerve Fibers Anatomy and Histology
          Optic Nerve Anatomy and Histology
          Neuropsychological Tests
          NIH Stroke Scale
          Scales
      ab: Objective To investigate the association between retinal nerve fiber layer (RNFL) thickness and cognitive dysfunction in patients with mild ischemic stroke. Methods Total 146 patients with mild ischemic stroke that diagnosed and treated in Chengde Central Hospital in Hebei from January 2020 to December 2021 were included. Optical coherence tomography (OCT) was used to measure the RNFL thickness in each quadrant of both eyes, and Mini -Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were used to evaluate cognitive function. Results In patients with mild ischemic stroke, the RNFL thickness at the superior side of left eye was greater than right eye (t = - 4.589, P = 0.000), and the RNFL thickness at the temporal side of right eye was greater than left eye (t = 3.639, P = 0.000). Correlation analysis showed that the correlation between the RNFL thickness at the superior side of the left eye and the MMSE score (r = 0.385, P = 0.000), the RNFL thickness at the temporal side of the left eye and the National Institutes of Health Stroke Scale (NIHSS) score at admission (r = 0.170, P = 0.020) were positively correlated. The correlation between the RNFL thickness at the inferior side of the left eye and the history of drinking (r = - 0.216, P = 0.011), the RNFL thickness at the temporal side of the right eye and the history of hypertension (r = - 0.194, P = 0.023) were negativley correlated. Conclusions The thinning of RNFL in patients with mild ischemic stroke may have a certain degree of association with cognitive dysfunction.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Chinese
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