Translating Evidence from Dutch Exercise Oncology Trials in Patients with Breast Cancer into Clinical Practice Using the RE-AIM Framework.

Purpose. We aimed to evaluate the potential for implementing exercise interventions for patients with breast cancer in the Netherlands, based on findings of the Dutch randomized controlled trials in this population. Methods. We evaluated the implementation of four Dutch exercise trials retrospective...

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Publicado en:European Journal of Cancer Care pp. 1 - 19
Autores principales: Ten Tusscher, Marieke R., Stuiver, Martijn M., Kampshoff, Caroline S., Huijsmans, Rosalie J., Aaronson, Neil K., Velthuis, Miranda, Gal, Roxanne, Van Waart, Hanna, May, Anne M., Buffart, Laurien M.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 11/10/2023
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: European Journal of Cancer Care
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      dt: 11/10/2023
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2023/2296881
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        atl: Translating Evidence from Dutch Exercise Oncology Trials in Patients with Breast Cancer into Clinical Practice Using the RE-AIM Framework.
      aug:
        au:
          Ten Tusscher, Marieke R.
          Stuiver, Martijn M.
          Kampshoff, Caroline S.
          Huijsmans, Rosalie J.
          Aaronson, Neil K.
          Velthuis, Miranda
          Gal, Roxanne
          Van Waart, Hanna
          May, Anne M.
          Buffart, Laurien M.
        affil: Radboud University Medical Center, Department of Medical BioSciences, Nijmegen, Netherlands
      sug:
        subj:
          Breast Neoplasms Therapy
          Therapeutic Exercise Netherlands
          Implementation Science
          Conceptual Framework
          Medical Practice
          Netherlands
          Aerobic Capacity
          Cancer Fatigue
          Quality of Life
          Patient Satisfaction
          Cost Effectiveness Analysis
          Descriptive Statistics
          Effect Size
          Patient Participation
          Treatment Outcomes
          Dose-Response Relationship
          Patient Compliance
          Insurance, Health, Reimbursement
          Physical Therapists
      ab: Purpose. We aimed to evaluate the potential for implementing exercise interventions for patients with breast cancer in the Netherlands, based on findings of the Dutch randomized controlled trials in this population. Methods. We evaluated the implementation of four Dutch exercise trials retrospectively, using the five dimensions of the RE-AIM framework: Reach (exercise participation rate), Effectiveness for physical fitness, fatigue, quality of life, and physical function, Adoption (e.g., satisfaction of physical therapists guiding the exercise intervention), Implementation (cost-effectiveness and exercise adherence correlates thereof), and Maintenance (maintenance of exercise levels by individual patients and sustainability of exercise delivery at organization level). Thereby, we reflect on these results using (international) literature to gain better insight in overall barriers, facilitators, and opportunities for further implementation of exercise interventions. Results. Participation rates of 44–52% not only indicated acceptable Reach in the context of a trial but also indicated room for improvement. Effectiveness of exercise during and after treatment was demonstrated in most trials showing benefits for aerobic fitness, physical fatigue, quality of life and physical function, and high patient satisfaction. Adoption of the exercise interventions by physical therapists was adequate (satisfaction score: 7.5 out of 10). Evaluation of Implementation indicated adequate adherence to supervised exercise, inconsistent findings on potential correlates of adherence, and promising results on cost-effectiveness. Currently, reimbursement for exercise programs is lacking. Maintenance of intervention effects at the patient level was limited and inconsistent. Maintenance of intervention availability at the organizational level was facilitated by an extensive network of specially trained physical therapists, but better communication and collaboration between different healthcare professionals are desired. Conclusions. Improved implementation could particularly be achieved by increasing reach and improved focus on exercise maintenance on both the patient and organizational level.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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