Fluorescence cholangiography for laparoscopic cholecystectomy: how, when, and why? A single-center preliminary study.

Bile duct injuries avoidance is a key goal of biliary surgery. In this prospective study we evaluate the safety and feasibility of ICG fluorescent cholangiography during laparoscopic cholecystectomy (LC) focusing on the optimization of timing and dose administration. From February to December 2022 f...

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Publicado en:Minimally Invasive Therapy & Allied Technologies Vol. 32; no. 5; pp. 264 - 273
Autores principales: Fassari, Alessia, Bianucci, Andrea, Lucchese, Sara, Santoro, Emanuele, Lirici, Marco Maria
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Oct2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2023
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      pub: Taylor & Francis Ltd
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        10.1080/13645706.2023.2265998
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        atl: Fluorescence cholangiography for laparoscopic cholecystectomy: how, when, and why? A single-center preliminary study.
      aug:
        au:
          Fassari, Alessia
          Bianucci, Andrea
          Lucchese, Sara
          Santoro, Emanuele
          Lirici, Marco Maria
        affil: Department of Surgical Oncology, San Giovanni-Addolorato Hospital, Rome, Italy
      sug:
        subj:
          Cholecystectomy, Laparoscopic Methods
          Cholangiography Methods
          Fluorescent Dyes Administration and Dosage
          Administration, Intravenous
          Human
          Biliary Tract Anatomy and Histology
          Retrospective Design
          Record Review
          Data Analysis Software
          Descriptive Statistics
          Bile Ducts Injuries
          Postoperative Complications
      ab: Bile duct injuries avoidance is a key goal of biliary surgery. In this prospective study we evaluate the safety and feasibility of ICG fluorescent cholangiography during laparoscopic cholecystectomy (LC) focusing on the optimization of timing and dose administration. From February to December 2022 fifty-four LC were performed with fluorescence imaging in our surgical department. 2.5 mg ICG were administered intravenously between 5 h and 24 h before surgery. Near-infrared fluorescent cholangiography (NIRF-C) was performed. Adequate fluorescence was evaluated by comparing agent accumulation in the gallbladder and the extrahepatic duct and the background of liver parenchyma. Biliary anatomy was identified in all cases. Median time of ICG administration was 11 h previous surgery and three groups of patients were identified: group A receiving ICG 5–9 h, group B 10–14 h, group C 15–24 h before surgery. Peak contrast was gained in group B, with minimal fluorescence of liver parenchyma and more intense visibility of the biliary tract. Intraoperative cholangiogram was unnecessary in all cases. Fluorescent cholangiography during LC is safe and feasible overcoming the limits of other techniques available. 2.5 mg ICG administered 10–14 h before surgery produces optimal outcomes for near-infrared (NIR) fluorescent cholangiography.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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