Association between vitamin D3 and some Biochemical parameters in Iraqi patients with chronic kidney disease.

Chronic kidney disease (CKD): is characterized by a decrease in kidney function manifested as evidenced by kidney disease or an estimated-glomerular filtration rate (eGFR) of less than (60)mL per minute per 1.73m² of body surface area for three or more months. Low levels of 25-hydroxyvitamin D and v...

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Publicado en:Revista Latinoamericana de Hipertensión Vol. 18; no. 8; pp. 354 - 362
Autores principales: Rashid, Teeba Ammar, Ali, Hameed Hussein, Hussein, Amer Jihad
Formato: Artículo
Publicado: Revista Latinoamericana de Hipertension 2023
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: Association between vitamin D3 and some Biochemical parameters in Iraqi patients with chronic kidney disease.
      aug:
        au:
          Rashid, Teeba Ammar
          Ali, Hameed Hussein
          Hussein, Amer Jihad
        affil:
          Chemistry Department, College of Science, University of Anbar.
          Ministry of Health, Anbar Health Directorate.
      su:
        Cholecalciferol
        Chronic kidney failure
        Chronically ill
        Vitamin D
        Receiver operating characteristic curves
        Kidney physiology
        Urea
      sug:
        subj:
          Cholecalciferol
          Chronic kidney failure
          Chronically ill
          Vitamin D
          Receiver operating characteristic curves
          Kidney physiology
          Urea
      ab:
        Chronic kidney disease (CKD): is characterized by a decrease in kidney function manifested as evidenced by kidney disease or an estimated-glomerular filtration rate (eGFR) of less than (60)mL per minute per 1.73m² of body surface area for three or more months. Low levels of 25-hydroxyvitamin D and vitamin D deficiency kidney disease are both a contributor to kidney disease. A study of the connections between vitamin D and a number of biochemical parameters such as concentration of Urea, PTH, Creatinine, eGFR, K+, Na+, Ca++, Mg++ and P in the serum. This study aims to examine concentrations of (OH) vitamin D level in CKD (pre-dialysis and post-dialysis). And this study aimed to find out receiver operating characteristic curve (ROC) each of vitamin D3, Urea, Creatinine and calcium pre and post dialysis. The study also aimed to identify the correlation between vitamin D and biochemical parameters. The mean of serum vit.D concentrations was lower in both groups: pre-dialysis (17.671±2.323)ng/ml, post-dialysis (15.543±1.731) ng/ml and there was highly significantly differences between these groups. There was a highly significant differences in concentrations of urea, creatinine, PTH, eGFR, Na+, K+, Ca++, Mg++ and p with CKD. Vitamin D had a significant negative correlation with BMI (p=0.038) in CKD patients, the p value (p≤0.05). vitamin D3 and Creatinine were shown to have a negative connection (P=0.001)
        Enfermedad renal crónica (ERC): se caracteriza por una disminución de la función renal que se manifiesta como una enfermedad renal o una tasa de filtración glomerular estimada (TFGe) inferior a (60) ml por minuto por 1,73 m2 de superficie corporal durante tres o más meses. Los niveles bajos de 25-hidroxivitamina D y la enfermedad renal por deficiencia de vitamina D contribuyen a la enfermedad renal. Un estudio de las conexiones entre la vitamina D y una serie de parámetros bioquímicos como la concentración de urea, PTH, creatinina, eGFR, K+, Na+, Ca++, Mg++ y P en el suero. Este estudio tiene como objetivo examinar las concentraciones de (OH) vitamina D en la ERC (prediálisis y posdiálisis). Y este estudio tuvo como objetivo conocer la curva característica operativa del receptor (ROC) de cada vitamina D3, urea, creatinina y calcio antes y después de la diálisis. El estudio también tuvo como objetivo identificar la correlación entre la vitamina D y los parámetros bioquímicos. La media de las concentraciones séricas de vit. D fue menor en ambos grupos: prediálisis (17,671±2,323)ng/ml, postdiálisis (15,543±1,731) ng/ml y hubo diferencias muy significativas entre estos grupos. Hubo diferencias muy significativas en las concentraciones de urea, creatinina, PTH, eGFR, Na+, K+, Ca++, Mg++ y p con ERC. La vitamina D tuvo una correlación negativa significativa con el IMC (p=0,038) en pacientes con ERC, el valor de p (p≤0,05). Se demostró que la vitamina D3 y la creatinina tienen una conexión negativa (P = 0,001).
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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