Early recurrences predict late therapy failure after pulsed field ablation of atrial fibrillation.
Introduction: Pulsed field ablation (PFA) is a new ablation technology for atrial fibrillation (AF). Data regarding early recurrences of atrial tachyarrhythmia (ERAT) after PFA‐pulmonary vein isolation (PVI) are sparse. Methods: Consecutive patients with symptomatic AF were enrolled to undergo PFA‐P...
| Published in: | Journal of Cardiovascular Electrophysiology Vol. 34; no. 12; pp. 2425 - 2434 |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | diagnostic images research tables/charts tracings Journal Article |
| Published: |
Wiley-Blackwell
Dec2023
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=174065165&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 174065165 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Dec2023 vid: 34 iid: 12 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 174065165 172370178 174065165 174065165 10.1111/jce.16083 174065165 ppf: 2425 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Early recurrences predict late therapy failure after pulsed field ablation of atrial fibrillation. aug: au: Plank, Karin Bordignon, Stefano Urbanek, Lukas Chen, Shaojie Tohoku, Shota Schaack, David Hirokami, Jun Efe, Tolga Chun, K.R. Julian Schmidt, Boris affil: Cardioangiologisches Centrum Bethanien CCB at Agaplesion Markus Krankenhaus, Medizinische Klinik III, Frankfurt am Main, Germany sug: subj: Atrial Fibrillation Surgery Recurrence Risk Factors Treatment Failure Tachycardia, Atrial Treatment Outcomes Evaluation Catheter Ablation Methods Risk Assessment Human Female Male Middle Age Aged Aged, 80 and Over Time Factors Kaplan-Meier Estimator Multivariate Analysis Confidence Intervals Sex Factors After Care Descriptive Statistics Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Female Male ab: Introduction: Pulsed field ablation (PFA) is a new ablation technology for atrial fibrillation (AF). Data regarding early recurrences of atrial tachyarrhythmia (ERAT) after PFA‐pulmonary vein isolation (PVI) are sparse. Methods: Consecutive patients with symptomatic AF were enrolled to undergo PFA‐PVI. A dedicated catheter delivering bipolar energy (1.9–2.0 kV) was used. Late recurrence (LR) was defined as documented AF/atrial tachycardia (AT) lasting more than 30 s after a 90‐day blanking period. Results: Two hundred and thirty‐one patients (42% female, age 69 ± 12, 55% paroxysmal AF [PAF]) were included in this analysis. Median follow‐up time was 367 days (interquartile range: 253–400). Forty‐six patients (21%) experienced ERAT after a median of 23 days (46% in PAF and 54% in persistent AF [persAF]). Kaplan–Meier estimated freedom of AF/AT was 74.2% at 1 year, 81.8% for PAF, and 64.8% for persAF (p =.0079). Of patients experiencing ERAT, an LR was observed in 54%. There was no significant difference of LR between those who presented with very early ERAT (0–45 days) and those with ERAT (46–90 days) (p =.57). In multivariate analysis, ERAT (hazard ratio [HR]: 3.370; 95% confidence interval [95% CI]: 1.851–6.136; p <.001) and female sex (HR: 2.048; 95% CI: 1.114–3.768; p =.021) were the only independent predictors for LR. Conclusions: ERAT could be recorded in 21% of patients after PFA‐PVI and was an independent predictor for LR. We found no difference in the rate of LRs among patients experiencing ERAT before or after 45 days. pubtype: Academic Journal doctype: diagnostic images research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|