Gas Humidification During Helmet Continuous Positive Airway Pressure: A Crossover Randomized Physiologic Study in Healthy Subjects.
Background: In the last decades, the use of the helmet interface to deliver noninvasive respiratory support has steadily increased. When delivering oxygen therapy, conditioning of inspired gas is mandatory, as the water content of medical gas is neglectable. To minimize the risk of airway damage, it...
| Published in: | Dimensions of Critical Care Nursing Vol. 43; no. 1; pp. 21 - 28 |
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| Main Authors: | , , , , , , , , , |
| Format: | pictorial research tables/charts randomized controlled trial Journal Article |
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Lippincott Williams & Wilkins
Jan/Feb2024
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=174099196&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 174099196 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07304625 48N jtl: Dimensions of Critical Care Nursing issn: 07304625 maglogo: N pubinfo: dt: Jan/Feb2024 vid: 43 iid: 1 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 174099196 174099196 174099196 10.1097/DCC.0000000000000616 174099196 ppf: 21 ppct: 7 formats: tig: atl: Gas Humidification During Helmet Continuous Positive Airway Pressure: A Crossover Randomized Physiologic Study in Healthy Subjects. aug: au: Ambrosetti, Lorenzo Giani, Marco Rezoagli, Emanuele Fiorillo, Chiara Vitale, Daniela Giacchè, Damiano Ravasio, Giambattista Fumagalli, Roberto Foti, Giuseppe Lucchini, Alberto affil: Lorenzo Ambrosetti, MD, is resident at the School of Medicine and Surgery, University of Milano-Bicocca, Monza, General Intensive Care Unit–ASST Monza, San Gerardo Hospital. sug: subj: Humidity Continuous Positive Airway Pressure Human Randomized Controlled Trials Random Assignment Confidence Intervals Ventilation Descriptive Statistics Data Analysis Software Crossover Design Physiological Studies Post Hoc Analysis ab: Background: In the last decades, the use of the helmet interface to deliver noninvasive respiratory support has steadily increased. When delivering oxygen therapy, conditioning of inspired gas is mandatory, as the water content of medical gas is neglectable. To minimize the risk of airway damage, it is recommended to achieve an absolute humidity greater than 10 mg H2O/L. The primary aim of the study was to assess the performance of 3 different heated humidifiers to condition gas during helmet continuous positive airway pressure and to compare them with a setting without active humidification. Methods: We performed a crossover randomized physiological study in healthy volunteers. Absolute humidity, relative humidity, and temperature were measured during 4 steps (no humidification and the 3 heated humidifiers, performed in a randomized order) and at 3 time points (after 1, 5, and 10 minutes). Results: Eight subjects participated to the study. Without active humidification, absolute humidity was constantly below the recommended level. All humidifiers conditioned the inspired gases to an average absolute humidity greater than 10 mg H2O/L. Overall, the best performance, in terms of absolute humidity, was obtained with H900 (19.74 ± 0.50 mg H2O/L), followed by TurbH2O (−6.82 mg H2O/L vs H900; 95% confidence interval, −8.49 to −5.14; P <.05) and F&P 810 (−9.03 mg H2O/L vs H900; 95% confidence interval, −10.70 to −7.35; P <.05). Conclusions: Active humidification is required to achieve adequate conditioning of inspired gas during helmet continuous positive airway pressure. The choice between different humidifiers available on the market should be made according to the local needs and expertise. pubtype: Academic Journal doctype: pictorial research tables/charts randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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