Skin Carotenoid Score as an Important Prognostic Factor for Predicting Type 2 Diabetes Mellitus in Middle-Aged Subjects.
This study aimed at identifying middle-aged subjects at risk for developing type 2 diabetes mellitus using noninvasive skin carotenoid and vascular function measurements. To this end, 61 subjects (40-65 years of age) without type 2 diabetes mellitus (Group A, Hemoglobin A1c < 6.5%) and 69 subjects (...
| Publicado en: | Current Topics in Nutraceutical Research Vol. 21; no. 4; pp. 373 - 380 |
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| Autores principales: | , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
New Century Health Publishers, LLC
Nov2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=174171750&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 174171750 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15407535 39NG jtl: Current Topics in Nutraceutical Research issn: 15407535 maglogo: N pubinfo: dt: Nov2023 vid: 21 iid: 4 pid: 35016 pub: New Century Health Publishers, LLC place: Denton, Texas artinfo: ui: 174171750 174171750 174171750 10.37290/ctnr2641-452X.21:373-379 174171750 ppf: 373 ppct: 7 formats: tig: atl: Skin Carotenoid Score as an Important Prognostic Factor for Predicting Type 2 Diabetes Mellitus in Middle-Aged Subjects. aug: au: Hans Hsientsai Wu Jian-Jung Chen Yi-Chuan Chen Haryadi, Bagus affil: Department of Electrical Engineering, National Dong Hwa University, No. 1, Sec. 2, Da Hsueh Rd., Hualien 97401, Taiwan sug: subj: Diabetes Mellitus, Type 2 Prognosis Carotenoids Blood Skin Diabetes Mellitus, Type 2 Risk Factors Risk Assessment Scales Human Noninvasive Procedures Cardiovascular System Physiology Evaluation Adult Middle Age Aged Spectrum Analysis Fruit Vegetables Food Intake Endothelium Physiology Heart Rate Variability Correlational Studies Metabolic Syndrome X Lipoproteins, HDL Waist Circumference Fasting Blood Glucose Glycated Hemoglobin Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years ab: This study aimed at identifying middle-aged subjects at risk for developing type 2 diabetes mellitus using noninvasive skin carotenoid and vascular function measurements. To this end, 61 subjects (40-65 years of age) without type 2 diabetes mellitus (Group A, Hemoglobin A1c < 6.5%) and 69 subjects (40-65 years of age) with type 2 diabetes mellitus (Group B, Hemoglobin A1c ≥ 6.5%) were recruited (Table 1). The skin carotenoid score was recorded using spectroscopy-based skin carotenoid measurements that approximate dietary fruit and vegetable intake. Endothelial function and heart rate variability were measured for the two groups and correlated with skin carotenoids scores. The daily vegetable and fruit intake was positively correlated with the skin carotenoids score in both groups (Group A, r = 0.598, p < 0.001; Group B, r = 0.449, p < 0.001). There were also significant differences in skin carotenoids score, indices of endothelial function, and heart rate variability between the subjects in group A and group B. There was a negative correlation between skin carotenoids score and individual determinants of metabolic syndrome, including high-density lipoprotein (r = -0.361, p = 0.009), waist circumference (r = -0.450, p < 0.001), fasting blood sugar (r = -0.713, p < 0.001), and Hemoglobin A1c (r = -0.808, p < 0.001); however, systolic blood pressure showed no significant correlation (p = 0.06). In conclusion, carotenoids and cardiovascular parameters are reliable predictive factors of type 2 diabetes mellitus in middle-aged subjects. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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